3.5.1.3	2-oxoglutaramate + H2O	-	
3.5.1.3	2-oxoglutaramate + H2O	alpha-ketoglutaramate	
3.5.1.3	2-oxoglutaramate + H2O	physiological function of omega-amidase might be hydrolysis or transfer of amide group of alpha-ketoglutarate	
3.5.1.3	2-oxoglutaramate + H2O	the in vivo substrates are generated by transamination of glutamine and asparagine, respectively	
3.5.1.3	2-oxoglutaramate + H2O	glutamine transaminase and omega-amidase potentially act in tandem to close the methionine salvage cycle in bacteria and plants	
3.5.1.3	2-oxosuccinamate + H2O	alpha-ketosuccinamate	
3.5.1.3	2-oxosuccinamate + H2O	the in vivo substrates are generated by transamination of glutamine and asparagine, respectively	
3.5.1.3	2-oxosuccinamate + H2O	the product of asparagine transamination, 2-oxosuccinamate, can be hydrolyzed by the enzyme omega-amidase to form oxaloacetate and ammonia	
3.5.1.3	additional information	-	
3.5.1.3	additional information	conversion of glutamine into alpha-ketoglutarate and ammonia is brought about by two distinct enzymes: glutamine transaminase and omega-amidase	
3.5.1.3	additional information	enzyme of glutamine-transaminase-omega-amidase pathway, role in degradation of glutamine	
3.5.1.3	additional information	enzyme, in conjunction with glutamine transaminase comprises enzyme system previously designated glutaminase II, involved in metabolism of glutamine	
3.5.1.3	additional information	second enzyme of the enzyme system capable of converting glutamine to ammonia and capable of generating relatively large amounts of ammonia from glutamine, the glutaminase II pathway, glutamine transaminase, EC 2.6.1.15 plus omega-amidase, EC 3.5.1.3 pathway	
3.5.1.3	additional information	pathway for brain glutamine metabolism involves glutamine transaminase-omega-maidase pathway, L-glutamine: 2-oxo-acid amino-transferase, EC 2.6.1.15 and omega-amidodicarboxylate amidohydrolase, EC 3.5.1.3	
3.5.1.3	additional information	role in cerebral glutamine metabolism	
3.5.1.3	additional information	high concentrations of omega-amidase in choroid plexus and in the S1-S3 region of nephron suggest that the glutaminase II pathway may generate appreciable ammonia locally in these organs, perhaps in association with transport	
3.5.1.3	additional information	glutamine-transaminase-omega-amidase pathway, metabolic role: utilization of glutamine, formation of ammonia, ammoniagenesis, and utilization of certain alpha-keto acids for synthesis of corresponding amino acids