3.5.1.13 3,4-dichloropropionanilide + H2O plants with significant amounts of aryl acylamidase are able to hydrolyze acylanilide herbicides quickly and thereby avoid the toxic effects of these compounds 3.5.1.13 4-acetamidophenol + H2O i.e. Tylenol 3.5.1.13 4-chloroacetanilide + H2O - 3.5.1.13 4-nitroacetanilide + H2O - 3.5.1.13 acetanilide + H2O - 3.5.1.13 additional information inducible enzyme 3.5.1.13 additional information constitutive enzyme 3.5.1.13 additional information induction by 2',6'-dimethylacetanilide 3.5.1.13 additional information induced by anilide, not subject to carbon or nitrogen repression by the growth medium 3.5.1.13 additional information inducible by various phenylamides of the acylanilide, phenylcarbamate, and methoxysubstituted phenylurea type 3.5.1.13 additional information key enzyme in plant herbicide detoxification 3.5.1.13 additional information induction by acetanilide, 2'-methylacetanilide, 3'-methylacetanilide, 4'-methylacetanilide 3.5.1.13 additional information strain MAB2: constitutive enzyme 3.5.1.13 additional information the aryl acylamidase activity, especially of butyrylcholinesterase, is involved in the development of the nervous system and in pathological processes such as the formation of neuritic plaques in Alzheimer's disease 3.5.1.13 additional information the aryl amide activity of the acetylcholinesterase has a distinct role in embryogenesis 3.5.1.13 additional information the reaction in human erythrocytes and plasma is performed by the butyrylcholinesterase, EC 3.1.1.8, which is inactive with butyrylthiocholine, also fatty acid free human albumin has aryl acylacylamidase activity, which accounts for 10% of total human enzyme activity 3.5.1.13 additional information 4-guanidinobutyramide probably is the natural substrate 3.5.1.13 phenacetin + H2O -