3.4.24.40 Fibrin + H2O - 3.4.24.40 Fibrinogen + H2O the enzyme hydrolyzes the Aalpha chain in 1 min, the Bbeta chain in 5 min, and the gamma chain in more than 1 h 3.4.24.40 human complement component C1 + H2O - 3.4.24.40 human complement component C2 + H2O - 3.4.24.40 additional information important factor in virulence seen in several microbial diseases caused by Pseudomonas aeruginosa and Serratia marcescens, e.g. corneal ulcers and pneumonia, inducible enzyme 3.4.24.40 additional information inhibits cytokine-induced signaling in A549 pulmonary epithelial cells 3.4.24.40 additional information inhibits IFN-gamma antiviral and immunomodulatory activity 3.4.24.40 additional information the enzyme does not degrade urokinase, streptokinase, and tissue plasminogen activator