3.2.1.31	curcumin-beta-D-glucuronide + H2O	curcumin, despite low systemic bioavailability, may be enzymatically activated (deconjugated) within GUSB-enriched bone to exert protective effects, a metabolic process that can also contribute to bone-protective effects of other highly glucuronidated dietary polyphenols	
3.2.1.31	dermatan sulfate + H2O	-	
3.2.1.31	heparan sulfate + H2O	-	
3.2.1.31	luteolin triglucuronide + H2O	-	
3.2.1.31	additional information	-	
3.2.1.31	additional information	role in physiology, in tissues, in body fluids	
3.2.1.31	additional information	activity is inducible by Met-Gly	
3.2.1.31	additional information	activity is not inducible by Met-Gly	
3.2.1.31	additional information	activity is slightly inducible by Met-Gly	
3.2.1.31	additional information	the potent beta-glucuronidase activity caused by the glucuronic acid conjugates from xenobiotics and endogenous compounds is a prime factor in the etiology of colon cancer	
3.2.1.31	additional information	when beta-glucuronidase producing bacteria infect the bile, the pH of the bile becomes raised, the high pH and bile induce the enzyme, and then bilirubin gallstones can be easily formed	
3.2.1.31	additional information	the enzyme is involved in glycosaminoglycan metabolism	
3.2.1.31	additional information	the beta-glucuronidase forms a complex with esterase 22 in the liver. Gus colocalizes with Es22 at the endoplasmic reticulum but does not affect its retinoyl ester hydrolase activity	
3.2.1.31	oestrone 3-glucuronide + H2O	-	
3.2.1.31	retinyl-beta-glucuronide + H2O	-