2.3.3.8	ADP + phosphate + acetyl-CoA + oxaloacetate	-	
2.3.3.8	ATP + citrate + CoA	-	
2.3.3.8	ATP + citrate + CoA	the cytosolic enzyme may provide acetyl-coenzyme A for the mevalonate pathway or fatty acid elongation	
2.3.3.8	ATP + citrate + CoA	enzyme is induced by starvation-refeeding regimen	
2.3.3.8	ATP + citrate + CoA	the plastidic enzyme is proposed to function for the supply of acetyl-coenzyme A for lipid biosynthesis de novo	
2.3.3.8	ATP + citrate + CoA	enzyme regulates both the direction and carbon flux of the carbon dioxide-fixing reductive tricarboxylic acid cycle	
2.3.3.8	ATP + citrate + CoA	the enzyme is regulated by the carbon source present in the medium	
2.3.3.8	ATP + citrate + CoA	enzyme generates cytosolic acetyl-CoA	
2.3.3.8	ATP + citrate + CoA	possibly plays a role in providing acetyl-CoA for lipid biosynthesis	
2.3.3.8	ATP + citrate + CoA	the enzyme is engaged in the transport of acetyl groups from mitochondria to cytosol. On the metabolic pathway from carbohydrate to lipid it is the first enzyme which is exclusively biosynthetic	
2.3.3.8	ATP + citrate + CoA	key enzyme of CO2 fixation by reductive tricarboxylic acid	
2.3.3.8	ATP + citrate + CoA	one of the key enzymes of lipogenesis	
2.3.3.8	ATP + citrate + CoA	the enzyme catalyzes the first cytoplasmic step in the synthesis of long-chain fatty acids in mammalian tissues	
2.3.3.8	ATP + citrate + CoA	the enzyme is responsible for production of cytoplasmic acetyl-CoA for lipogenesis	
2.3.3.8	ATP + citrate + CoA	key enzyme for lipid accumulation	
2.3.3.8	ATP + citrate + CoA	acetyl-CoA is produced in mitochondria, but it cannot cross the mitochondrial membranes to the cytosol. Instead, citrate is exported from mitochondria. In the cytosol, ATP-citrate lyase (ACLY; EC 2.3.3.8) catalyses the reaction to produce acetyl-CoA and oxaloacetate from citrate and ATP	
2.3.3.8	ATP + citrate + CoA	acetyl-coenzyme A (acetyl-CoA) generated by ATP citrate lyase (ACL) is utilized to acetylate histone H3 at MyoD regulatory regions, resulting in increased MyoD expression and improved muscle regeneration after injury	
2.3.3.8	ATP + citrate + CoA	ATP citrate lyase is an important enzyme linking carbohydrate to lipid metabolism by generating acetyl-CoA from citrate for fatty acid and cholesterol biosynthesis	
2.3.3.8	ATP + citrate + CoA	essential enzyme for generating acetyl-CoA, a key metabolite for the first step in fatty acid synthesis and for histone acetylation. Regulation of the enzyme activity is a potentially important point of control for cell cycle regulation in the myeloid lineage	
2.3.3.8	ATP + citrate + CoA	the enzyme catalyzes the formation of cytosolic acetyl CoA, the starting material for de novo lipid and cholesterol biosynthesis	
2.3.3.8	ATP + citrate + CoA	the enzyme is a major source of nucleocytosolic acetyl-CoA, a fundamental building block of carbon metabolism in eukaryotes	
2.3.3.8	ATP + citrate + CoA	the enzyme links carbohydrate and lipid metabolism	
2.3.3.8	ATP + citrate + CoA	the enzyme links glycolysis to lipid metabolism	
2.3.3.8	ATP + citrate + CoA	the enzyme synthesizes cytosolic acetyl coenzyme A (acetyl-CoA), a fundamental cellular building block	
2.3.3.8	additional information	enzyme is a nonredundant source of cytosolic acetyl-CoA