1.3.98.1 (S)-dihydroorotate + acceptor fourth step in synthesis of pyrimidine nucleotides 1.3.98.1 (S)-dihydroorotate + acceptor fourth step in UMP-biosynthesis 1.3.98.1 (S)-dihydroorotate + fumarate - 1.3.98.1 (S)-dihydroorotate + fumarate enzyme is responsible for biosynthesis of succinate and orotate 1.3.98.1 (S)-dihydroorotate + O2 pathway of pyrimidine biosynthesis, constitutive biosynthetic enzyme 1.3.98.1 L-dihydroorotate + fumarate - 1.3.98.1 L-dihydroorotate + fumarate DHODH catalyzes a coupled redox reaction in which dihydroorotate is oxidized to orotate and fumarate is reduced to succinate