6.5.1.3	ATP + (ribonucleotide)n + (ribonucleotide)m	the enzyme is essential for survival of both insect and bloodstream forms of the parasite	
6.5.1.3	ATP + (ribonucleotide)n + (ribonucleotide)m	the L1 ligase is regioselective for formation of the biologically relevant 5' to 3' phosphodiester bond rather than a 5' to 2' bond	
6.5.1.3	ATP + (ribonucleotide)n + (ribonucleotide)m	Trl1 executes the end-healing and end-sealing steps of tRNA splicing, requires a 2'-PO4 end for tRNA splicing in vivo	
6.5.1.3	ATP + (ribonucleotide)n + (ribonucleotide)m	possibly involved in posttranscriptional RNA editing process of mitochondrial transcripts	
6.5.1.3	ATP + (ribonucleotide)n-3'-hydroxyl + 5'-phospho-(ribonucleotide)m	-	
6.5.1.3	ATP + [RNA ligase]-L-lysine	-	
6.5.1.3	additional information	the group I intron from cyanobacterium Anabaena sp. catalyzes phosphodiester bond formation using a triphosphate on the 5'-terminal nucleotide, much like protein polymerases and engineered ribozymes. In the process, this ribozyme forms a unique circular RNA that incorporates the exogenous guanosine cofactor added during self-splicing