3.5.4.4	adenosine + H2O	the enzyme is involved in differentiation and maturation of the lymphoid system, the enzyme activity is decreased in multiple sclerosis patients irrespective of whether patients have relapsing-remitting or chronic progressive multiple sclerosis, overview	
3.5.4.4	adenosine + H2O	the enzyme is involved in the bile duct-inflammation and fibrosis caused chronic fascioliasis including an atrophy of the liver parenchyma and liver cirrhosis	
3.5.4.4	adenosine + H2O	the enzyme plays an important role in the immune system	
3.5.4.4	adenosine + H2O	adenosine deaminase is involved in purine metabolism and is a key enzyme for the control of the cellular levels of adenosine	
3.5.4.4	adenosine + H2O	adenosine deamination is involved in the essential pathway of purine salvage in Plasmodium falciparum, and inhibition of purine salvage results in parasite death	
3.5.4.4	adenosine + H2O	metabolization of extracellular adenosine leads to exacerbation of inflammation	
3.5.4.4	adenosine + H2O	the enzyme is important in thymocyte development, especially in late stages, overview	
3.5.4.4	adenosine + H2O	ADA, nucleotide metabolism	
3.5.4.4	adenosine + H2O	key enzyme involved in the purine metabolism	
3.5.4.4	additional information	regulatory role of dipeptidyl peptidase IV on adenosine deaminase activity