2.7.11.18 additional information myosin light-chain kinase contributes to the proliferation and migration of breast cancer cells through cross-talk with activated ERK1/2, overview 2.7.11.18 additional information PKA regulates beta2-integrin avidity activation via a MLCK-dependent pathway, overview 2.7.11.18 additional information postnatal decreases in vascular reactivity involve decreases in the thick filament component of myofilament calcium sensitivity, which is measured as the relationship between cytosolic calcium concentration and myosin light chain phosphorylation, relations between myosin light chain phosphorylation and contractile force, overview 2.7.11.18 additional information the enzyme is involved in inflammation response, including apoptosis, vascular permeability, and leukocyte diapedesis. Single nucleotide polymorphisms are involved in the risk of sepsis-related acute lung injury and asthma 2.7.11.18 additional information 14-3-3 binding of nmMLCK 2.7.11.18 additional information non-muscle myosin and smooth muscle myosin are the only known substrates of MLCK in vivo