6.2.1.1 Ca2+ 10 mM, can replace Mg2+ in activation, with 30% of the efficiency relative to Mg2+ 553 6.2.1.1 Ca2+ about 30% of the activation with Mg2+ or Mn2+ 671665 6.2.1.1 Ca2+ about 70% of the activation with Mg2+ or Mn2+, AF-ACS2 671665 6.2.1.1 Ca2+ can replace Mg2+ in activation, with 50% of the efficiency relative to MgCl2 568 6.2.1.1 Ca2+ Km for CaCl2 is 1.2 mM 568 6.2.1.1 Ca2+ two types of divalent metal ion requirement, 1. Mg2+, Mn2+, Fe2+, Co2+ or Ca2+ required for the formation of the enzyme-bound acetyl adenylate, 2. Ni2+, Cd2+, Fe2+ or Cu2+ required for adenylate binding 563 6.2.1.1 Cd2+ two types of divalent metal ion requirement, 1. Mg2+, Mn2+, Fe2+, Co2+ or Ca2+ required for the formation of the enzyme-bound acetyl adenylate, 2. Ni2+, Cd2+, Fe2+ or Cu2+ required for adenylate binding 563 6.2.1.1 Co2+ about 70% of the activation with Mg2+ or Mn2+, AF-ACS2 671665 6.2.1.1 Co2+ about 80% of the activation with Mg2+ or Mn2+ 671665 6.2.1.1 Co2+ can replace Mg2+ in activation, 50% as effective as MgCl2, Km for CoCl2 is 0.2 mM 568