3.6.1.71 additional information DNA deadenylation activity is metal-independent 754082 3.6.1.71 Zn2+ binding of Aptx to duplex DNA is mediated by the C-terminal zinc finger domain, and efficient deadenylation requires the zinc finger 754079 3.6.1.71 Zn2+ required 750417 3.6.1.71 Zn2+ required, the APTX Zn2+-binding betabetaalpha core is structurally related to the ubiquitous family of DNA binding C2H2 transcription factors including the prototypical Zif268 752086