3.4.24.27	Ba2+	activates 8% at 1 mM, 15% at 5 mM	734335	
3.4.24.27	Ca2+	-	683276, 683691	
3.4.24.27	Ca2+	4 calcium ions required for structural stability	651799	
3.4.24.27	Ca2+	activates 36% at 1 mM, 48% at 5 mM	734335	
3.4.24.27	Ca2+	CaCl2 does not exert any significant influence on the activity of immobilized thermolysin, but stabilizes the enzyme in absence of Zn2+	733524	
3.4.24.27	Ca2+	contains 4 structural calcium ions	649825	
3.4.24.27	Ca2+	four Ca2+ ions are required for thermostability	711460	
3.4.24.27	Ca2+	four Ca2+ per enzyme molecule are required for enzyme stability	683276	
3.4.24.27	Ca2+	four ions per enzyme molecule required for stability	683182, 683615, 683616, 683687, 684019	
3.4.24.27	Ca2+	protease binds calcium ions in the regions that are involved in the autolytic maturation process, at least one of the calcium ions plays a regulatory role. This calcium ion plays an important role as a switch that modulates the protease between stable and unstable states as appropriate to the biological need	718367