1.14.16.4	Ca2+	activates TPH2 promoter activity	688507	
1.14.16.4	Ca2+	the calcium influx through L-type high voltage-activated calcium channels is essential for the full activation of tryptophan hydroxylase leading to melatonin synthesis in the pineal gland	688765	
1.14.16.4	Fe2+	-	714213, 716436	
1.14.16.4	Fe2+	0.02 mM, 3.5fold increase in activity	438662	
1.14.16.4	Fe2+	5fold increase in activity	438658, 438661	
1.14.16.4	Fe2+	enzyme from pineal gland, stimulation	438654	
1.14.16.4	Fe2+	Fe2+ concentration for half-maximal activation of recombinant N-terminal truncated enzyme: 0.0013 mM	438676	
1.14.16.4	Fe2+	N- and C-terminal recombinant enzyme, iron is required for activity	438672	
1.14.16.4	Fe2+	not required for full activity	438664	
1.14.16.4	Fe2+	recombinant pineal enzyme contains 0.2-0.3 mol of iron/mol of enzyme	438675