4.6.1.12 Co2+ preferred 708124 4.6.1.12 Mg2+ dependent on 656498 4.6.1.12 Mg2+ Mg2+ or Mn2+ are required 655417 4.6.1.12 Mg2+ Mg2+ or Mn2+, positioned between the alpha- and beta-phosphates of the substrate, acts in concert with the Zn2+ to align and polarize the substrate for catalysis 709435 4.6.1.12 Mg2+ Mn2+ or Mg2+ required 657177 4.6.1.12 Mg2+ preference 708124 4.6.1.12 Mg2+ preferred 708124 4.6.1.12 Mn2+ - 663548 4.6.1.12 Mn2+ a Mn2+ with octahedral geometry, is positioned between the alpha and beta phosphates acting in concert with the Zn2+ to align and polarize the substrate for catalysis 657196 4.6.1.12 Mn2+ Mg2+ or Mn2+ are required 655417