3.6.1.67	Co2+	excellent mimic of Mg2+	758154	
3.6.1.67	Mg2+	dependent on	758154	
3.6.1.67	Mg2+	divalent cations are rerquired for the enzyme to function. Maximal activation is achieved with 8 mM Mg2+. Zn2+ and Ca2+ (both at 8 mM) are 2.4% and 7.1%, respectively, as effective as Mg2+. Mn2+ can not be tested because 7,8-dihydroneopterin triphosphate is rapidly and nonenzymatically decomposed in the presence of Mn2+	727800	
3.6.1.67	Mg2+	maximal activation is achieved with 8 nM Mg2+. Zn2+ and Ca2+ (both at 8 mM) are 2.4% and 7.1%, respectively, as effective as Mg2	727800	
3.6.1.67	Mg2+	required, no activity with Ca2+	727852	
3.6.1.67	Mg2+	requires a physiological level (approximately 1 mM) of Mg2+	727852	
3.6.1.67	Mg2+	the enzyme requires a physiological level of Mg2+, 70% of its maximal activity is reached at 1 mM Mg2+. No activation by 1 mM Ca2+	727852	
3.6.1.67	Ni2+	excellent mimic of Mg2+	758154