3.4.21.92 Ca2+ poor substitute for Mg2+ 29858, 29860 3.4.21.92 Mg2+ ClpA degrades large proteins down to short peptides of 7 to 10 amino acids, the process requires both Mg2+ and ATP hydrolysis 653260 3.4.21.92 Mg2+ optimal concentration: 5.1 mM 29860 3.4.21.92 Mg2+ proteolytic activity of ClpAP is dependent on, concentrations higher than about 30 mM are inhibitory 29858 3.4.21.92 Mn2+ can partially substitute for Mg2+ 29860 3.4.21.92 Zn2+ poor substitute for Mg2+ 29858