3.4.15.1 CaCl2 activates in absence of Cl-, maximal activity at 0.3 mM 81235 3.4.15.1 Cl- the activity of the C-domain of sACE depends highly on chloride ion concentration and is inactive in its absence, whereas the N-domain can be completely activated at relatively low concentrations of this anion and is still active in the absence of chloride 708830 3.4.15.1 Co2+ activates, but to a lesser extent than Zn2+ 755273 3.4.15.1 Co2+ activation 81260, 81285, 81287 3.4.15.1 Co2+ CoCl2 stimulates 81269 3.4.15.1 CoCl2 0.1-1.0 mM, 2fold activation 650873 3.4.15.1 KBr activation is lower than with NaCl 81264 3.4.15.1 KI activation is lower than with NaCl 81264 3.4.15.1 Mn2+ activates, but to a lesser extent than Zn2+ 755273 3.4.15.1 additional information enzyme is not affected by addition of 0.1-1.0 mM CaCl2, Mn2Cl2, MgCl2 or 0.1 mM ZnCl2 650873