2.1.1.14 Ca2+ can replace Mg2+ 441326 2.1.1.14 cadmium Cd2+ may replace the Zn2+ ion in the active site 755889 2.1.1.14 Mg2+ at low phosphate concentration, 0.1 mM, the Mg2+-stimulation is 4.5fold, smaller stimulation at higher concentrations of phosphate 441323 2.1.1.14 Mg2+ no stimulation 441326, 441337 2.1.1.14 Mg2+ required 441172 2.1.1.14 Mg2+ stimulates 441322, 441323, 441326 2.1.1.14 Mn2+ below 1 mM more effective than Mg2+, above 1 mM inhibitory 441172 2.1.1.14 phosphate - 441172, 441322, 441323, 441326, 441328, 441337 2.1.1.14 Zinc enzyme contains zinc 657437 2.1.1.14 Zinc required for activation and binding of L-homocysteine 660333