1.17.1.9 Ca2+ 1 mM Ca2+ improves the enzyme activity by 77% 724094 1.17.1.9 Ca2+ the enzyme activity is increased 13.8% over the control by 1 mM Ca2+ 725222 1.17.1.9 Co2+ 1 mM Co2+ improves the enzyme activity by 46% 724094 1.17.1.9 Co2+ the enzyme activity is increased 9.8% over the control by 1 mM Co2+ 725222 1.17.1.9 Fe 5-8 mol of iron per mol of enzyme 288087 1.17.1.9 Fe contains 11-18 gatoms of non-heme iron per mol of enzyme 288083 1.17.1.9 Fe formate dehydrogenase I contains 18-25 mol of iron per mol of enzyme. Formate dehydrogenase II contains 6-10 mol of iron per mol of enzyme 288092 1.17.1.9 Fe two distinct [Fe-S] centres 288120 1.17.1.9 Fe2+ the enzyme activity is increased 49.4% over the control by 1 mM Fe2+ 725222 1.17.1.9 Iron contains 5 mol nonheme iron per mol of enzyme. The beta-subunit contains a putative binding motif for an iron-sulfur cluster. The alpha-subunit contains at least one iron-sulfur cluster 655461