4.1.3.1 Ni2+ no activity in absence of exogenous cation, Ni2+ 7% as effective as Mg2+ 33117 4.1.3.1 Sr2+ no activation 33147, 33148 4.1.3.1 Sr2+ no activity in absence of exogenous cation, Sr2+ 3% as effective as Mg2+ 33117 4.1.3.1 Zn2+ 5 mM, 90% inhibition of Mg2+-activated enzyme, interaction with catalytic domain induces partial unfolding (revealed by thermal denaturation, far-UV circular dichroism, ANS fluorescence spectra, and glutaraldehyde crosslinking) 701127