3.5.3.22 Co2+ preferred metal activator 3.5.3.22 Mn2+ enhances activity 3.5.3.22 Mn2+ 50% of the activity with Co2+ as activator 3.5.3.22 additional information no activation by Ca2+, Fe2+ and Zn2+ 3.5.3.22 Ni2+ 50% of the activity with Co2+ as activator