2.4.1.117 Ca2+ CaCl2 cannot replace MgCl2 or MnCl2 488486 2.4.1.117 Ca2+ divalent cation required, efficiency of activiation in descending order: Mg2+, Mn2+, Ca2+, Co2+, Zn2+ 488483 2.4.1.117 Ca2+ divalent cation required, maximum stimulation in presence of Ca2+. Co2+, Mg2+ or Mn2+ can replace Ca2+ 488485 2.4.1.117 Ca2+ no stimulation 488488, 488492 2.4.1.117 Co2+ divalent cation required, efficiency of activiation in descending order: Mg2+, Mn2+, Ca2+, Co2+, Zn2+ 488483 2.4.1.117 Co2+ divalent cation required, maximum stimulation in presence of Ca2+. Co2+, Mg2+ or Mn2+ can replace Ca2+ 488485 2.4.1.117 Mg2+ divalent cation required, efficiency of activiation in descending order: Mg2+, Mn2+, Ca2+, Co2+, Zn2+ 488483 2.4.1.117 Mg2+ divalent cation required, either Mg2+ or Mn2+, Mn2+ stimulates the enzyme to a greater extent than Mg2+ at low concentrations, Mg2+ stimulates to a greater extent than Mn2+ at high concentration, but each is maximally effective at a concentration around 8 mM 488480 2.4.1.117 Mg2+ divalent cation required, maximum stimulation in presence of Ca2+. Co2+, Mg2+ or Mn2+ can replace Ca2+ 488485 2.4.1.117 Mg2+ Km: 0.7 mM 488483, 488487 2.4.1.117 Mg2+ Mg2+ required, not Mn2+, Ca2+ 488488 2.4.1.117 Mg2+ Mg2+ stimulates 488492 2.4.1.117 Mn2+ divalent cation required, efficiency of activiation in descending order: Mg2+, Mn2+, Ca2+, Co2+, Zn2+ 488483 2.4.1.117 Mn2+ divalent cation required, either Mg2+ or Mn2+, Mn2+ stimulates the enzyme to a greater extent than Mg2+ at low concentrations, Mg2+ stimulates to a greater extent than Mn2+ at high concentration, but each is maximally effective at a concentration around 8 mM 488480 2.4.1.117 Mn2+ divalent cation required, maximum stimulation in presence of Ca2+. Co2+, Mg2+ or Mn2+ can replace Ca2+ 488485 2.4.1.117 Mn2+ MnCl2 stimulates at 1 mM, inhibits at higher concentration 488486 2.4.1.117 Mn2+ no stimulation 488488, 488492 2.4.1.117 Zn2+ divalent cation required, efficiency of activiation in descending order: Mg2+, Mn2+, Ca2+, Co2+, Zn2+ 488483