1.8.4.2	Cs+	0.3 M: activates	
1.8.4.2	Cu2+	human COA6 binds Cu with high affinity in vitro	
1.8.4.2	Mn2+	1 mM: activates	
1.8.4.2	phosphate	enhances activity	
1.8.4.2	Zn2+	essential for activity