1.14.11.6	Fe2+	-	
1.14.11.6	Fe2+	4 residues within this motif are critical for the coordination of Fe2+ and 2-oxoglutarate binding as well as functionality of this family of enzymes	
1.14.11.6	Fe2+	acts as cofactor, 4 residues within this motif are critical for the coordination of Fe2+ and 2-oxoglutarate binding as well as functionality of this family of enzymes	
1.14.11.6	Fe2+	dependent on, required for catalysis	
1.14.11.6	additional information	Ni2+ and Ca2+ cannot substitute for Fe2+, binding structure with truncated enzyme mutant. Residues His214, Asp216 and His271 play essential roles in the metal ion binding	
1.14.11.6	Fe2+	non-heme