1.1.3.15 Ag+ up to 4fold induction 1.1.3.15 Cd2+ induction 1.1.3.15 Cu2+ exposure of cells to mM copper sulfate, strong induction. Highest induction at 0.3 mM, about 16-fold increase in activity. Identification of a copper-response element in the 5'-region of the LctO gene 1.1.3.15 CuSO4 induces copper regulated promoter, upregulates LctO 17fold (2D gel) 1.1.3.15 additional information Zn2+, Fe2+, Ni2+, Mn2+, and Ca2+ have no significant effect on lctO expression