6.5.1.3	Mg2+	optimum activity at 5 mM	653392	
6.5.1.3	Mg2+	required	1910, 1983, 1995	
6.5.1.3	Mg2+	requires metal ions for structure and catalysis	650172	
6.5.1.3	Mg2+	the active site contains two metal ions, consistent with the two-magnesium ion catalytic mechanism	674568	
6.5.1.3	Mn2+	activates, showing slightly higher activity than Mg2+	662976	
6.5.1.3	Mn2+	enzyme activity is optimal at 2.5 mM Mn2+	749277	
6.5.1.3	Mn2+	Mg2+ or Mn2+ required	662241	
6.5.1.3	Mn2+	only marginal activity	650172	
6.5.1.3	Mn2+	optimum activity at 1 mM	653392	
6.5.1.3	Mn2+	the enzyme prefers manganese as the metal cofactor for nick sealing	749172