1.7.2.1	cell membrane	associated with	-	665353	
1.7.2.1	cytoplasm	important differences in the primary structure of the cytoplasmic enzyme form and the extracellularv enzyme form, indicating that Haloferax mediterranei could carry out a maturation and exportation process within the cell before the protein is exported to the S-layer. Several conserved signals found in Cu-NirK from Haloferax mediterranei sequence indicate that these processes are closely related to the Tat system	5737	-, 727084	
1.7.2.1	extracellular	enzyme is released from bacteria, after exposure to different antimicrobial agents	-	-, 663639	
1.7.2.1	extracellular	important differences in the primary structure of the cytoplasmic enzyme form and the extracellularv enzyme form, indicating that Haloferax mediterranei could carry out a maturation and exportation process within the cell before the protein is exported to the S-layer. Several conserved signals found in Cu-NirK from Haloferax mediterranei sequence indicate that these processes are closely related to the Tat system	-	-, 727084	
1.7.2.1	membrane	-	16020	-, 727084	
1.7.2.1	membrane	equally distributed between the soluble- and the membrane fraction	16020	394526	
1.7.2.1	mitochondrion	-	5739	742855	
1.7.2.1	mitochondrion	the first 65 amino acid residues of theN-terminal domain constitute a mitochondrial targeting signal, sequence analysis	5739	695769	
1.7.2.1	periplasm	-	-	-, 395063, 395065, 395066, 658738, 659035, 660459, 698810, 742802	
1.7.2.1	periplasm	75% of enzyme activity found in the soluble fraction	-	395065