2.7.1.154	actin filament	-	5884	761736	
2.7.1.154	clathrin-coated vesicle	-	30136	761736	
2.7.1.154	clathrin-coated vesicle	PI3K-C2alpha is closely associated with clathrin-coated pits and vesicles through its direct interaction via its N-terminal clathrin-binding domain	30136	761736	
2.7.1.154	clathrin-coated vesicle	PI3KC2alpha	30136	645037, 645044	
2.7.1.154	Golgi trans-face	-	-	645044	
2.7.1.154	juxtanuclear Golgi region	at high levels	-	640950	
2.7.1.154	membrane	-	16020	739146	
2.7.1.154	membrane	predominantly localised to intracellular membranes	16020	672858	
2.7.1.154	additional information	both PI3K-C2alpha and PI3K-C2beta are co-localized with clathrin-coated pits and vesicles. PI3K-C2beta, but not PI3K-C2alpha, is highly co-localized with actin filament-associated clathrin-coated structures and required for actin filament formation at the clathrin-coated structures	-	761736	
2.7.1.154	additional information	membrane translocation of PI3K-C2alpha in response to KCl	-	760780	
2.7.1.154	additional information	the recombinant enzyme is localized mainly in the low density microsomal fraction, with a small amount being present in the plasma membrane and the cytosolic fraction	-	640862	
2.7.1.154	nuclear membrane	at low level	31965	640950	
2.7.1.154	nucleus	-	5634	671183	
2.7.1.154	plasma membrane	-	5886	761670	
2.7.1.154	plasma membrane	at low level	5886	640950	
2.7.1.154	plasma membrane	colocalization of the enzyme with plasma membrane-coated pits in COS-cells	5886	-, 645040	
2.7.1.154	plasma membrane	constitutively associated with phospholipid membranes	5886	-, 645044	
2.7.1.154	plasma membrane	renal brush-border and basal lateral, enzyme form phosphoinositide 3-kinase C2beta occurs only in renal brush-border plasma membrane	5886	660945	
2.7.1.154	vesicle	-	31982	761736	
2.7.1.154	vesicle	existence of PI3K-C2alpha and 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate on CD63-positive large vesicles in FceRI-stimulated RBL-2H3 cells	31982	739499