2.3.1.B41	chromatin	-	785	758437	
2.3.1.B41	nucleosome	-	786	755787	
2.3.1.B41	nucleosome	SIRT6 activity is nucleosome dependent, and suggest that its binding to the nucleosome might convert it into an active structure	786	730498	
2.3.1.B41	intracellular	-	5622	756689	
2.3.1.B41	nucleus	-	5634	755787, 756392, 756407, 756672, 756689, 757236, 757931, 758437	
2.3.1.B41	nucleus	during interphase, Sirt6 is mostly localized to the nucleus	5634	730527	
2.3.1.B41	nucleus	SIRT6 and Per2 co-localize in the nucleus	5634	755978	
2.3.1.B41	nucleus	the C-terminus of SIRT6 is required for nuclear localization of the enzyme	5634	755918	
2.3.1.B41	nucleolus	Sirt6 is enriched in the nucleolus in the G1 phase of the cell cycle, while S phase nucleoli are almost entirely free of Sirt6	5730	730527	
2.3.1.B41	mitochondrion	-	5739	-, 756973	
2.3.1.B41	cytoplasmic stress granule	SIRT6 translocates into the cytoplasm under stress and regulates formation as well as disassembly of stress granules	10494	730101	
2.3.1.B41	mitotic spindle	Sirt6 partially colocalizes with mitotic spindles	72686	730527