1.14.17.3 cytoplasm - 5737 438587 1.14.17.3 cytoplasm peptidylglycine alpha-hydroxylating activity and peptidylhydroxylglycine N-C lyase activity 5737 438583 1.14.17.3 cytoplasm soluble form 5737 438586 1.14.17.3 cytosol - 5829 699036 1.14.17.3 endoplasmic reticulum membrane integral membrane enzyme 5789 745327 1.14.17.3 extracellular - - 699036 1.14.17.3 extracellular recombinant enzyme secreted into medium - 438589, 438591, 438594 1.14.17.3 Golgi apparatus quantification of PAM endocytic trafficking to the trans-Golgi network 5794 745327 1.14.17.3 membrane - 16020 438579, 438581, 659916, 699036 1.14.17.3 membrane enzyme PAM is a type I integral membrane protein 16020 745296 1.14.17.3 membrane from neurosecretory vesicles 16020 438587 1.14.17.3 membrane integral membrane 16020 438587 1.14.17.3 membrane particulate form, except for abdominal ganglia 16020 438586 1.14.17.3 membrane recombinant bifunctional enzyme form 2, uncleaved in insect cells 16020 438583 1.14.17.3 membrane transmembranal protein 16020 438584 1.14.17.3 membrane transmembrane protein with lumenal and cytoplasmic parts, overview, abundant in atrial secretory vesicles 16020 658458 1.14.17.3 additional information distribution of membrane-bound and soluble peptidylglycine alpha-hydroxylating activity - 438587 1.14.17.3 additional information localization around the nuclei - 658685 1.14.17.3 additional information the enzyme is localized to the perinuclear region in a complex reticular pattern resembling that of the Golgi complex - 745296 1.14.17.3 secretory granule - 30141 438562, 438564, 438570, 438572, 745296, 745332 1.14.17.3 secretory granule chromaffin granules 30141 438568, 438581 1.14.17.3 secretory granule synaptosomal and neurosecretory granules 30141 438565 1.14.17.3 secretory vesicle - 99503 728832 1.14.17.3 trans-Golgi network - 5802 728832 1.14.17.3 vesicle from atrial myocytes, enzyme is recruited by aggregates of pro-atrial natriuretic peptide proANP, N-terminally deleted proANP is inhibited in recruiting the enzyme 31982 658458 1.14.17.3 vesicle neurosecretory 31982 658976