1.14.11.16 cytoplasm - 5737 659316 1.14.11.16 cytoplasm the pattern of diffuse cytoplasmic staining iss reticular or particulate, consistent with the known microsomal and mitochondrial distributions of the enzyme 5737 743130 1.14.11.16 endoplasmic reticulum - 5783 742666 1.14.11.16 endoplasmic reticulum membrane-anchored enzyme, whose C-terminal oxygenase and tetratricopeptide repeat domains present in the ER lumen 5783 765446 1.14.11.16 membrane membrane-associated 16020 725118 1.14.11.16 membrane transmembrane protein 16020 743882 1.14.11.16 membrane type 2 transmembrane protein. The enzyme can translocate to cell membrane from the endoplasmic reticulum membrane when it is overexpressed in cancer cell, which hydroxylate proteins such as Notch, Jagged, and cellular adhesion molecules that regulate cell migration and invasion 16020 742226 1.14.11.16 microsome - - 439260 1.14.11.16 mitochondrion - 5739 743376 1.14.11.16 additional information L-cell extract - 439260 1.14.11.16 plasma membrane - 5886 742666 1.14.11.16 rough endoplasmic reticulum - 5791 439259