4.1.1.90 additional information - additional information Km-values measured by hyperbolic weighted least-squares analysis 696184 4.1.1.90 0.0017 - 28-residue peptides based on residues -18 to +10 of human proprothrombin pH 7.0 697705 4.1.1.90 0.0023 - YVFLDHQDADANLILNRPKR FLAG-vitamin K-dependent gamma-glutamyl carboxylase 438309 4.1.1.90 0.0038 - vitamin KH2 proPT28, R406A/H408A mutant 438309 4.1.1.90 0.004 - vitamin KH2 proPT28, FLAG-vitamin K-dependent gamma-glutamyl carboxylase 438309 4.1.1.90 0.0041 - YVFLDHQDADANLILNRPKR R359A/H360A/K361A mutant 438309 4.1.1.90 0.0052 - YVFLDHQDADANLILNRPKR R406A/H408A mutant 438309 4.1.1.90 0.006 - proFactor IX pH 7.0 697705 4.1.1.90 0.0068 - TVFLDHENANKILNRPKRANTBLEEVRK carboxylase probe1, TVFLDHENANKILNRPKRANTBLEEVRK as a substrate 697924 4.1.1.90 0.007 - vitamin KH2 proPT28, R234A/H235A mutant 438309 4.1.1.90 0.0081 - YVFLDHQDADANLILNRPKR R234A/H235A mutant 438309 4.1.1.90 0.0123 - vitamin KH2 proPT28, R513A/K515A mutant 438309 4.1.1.90 0.0144 - YVFLDHQDADANLILNRPKR R513A/K515A mutant 438309 4.1.1.90 0.032 - vitamin KH2 FLEEL, R513A/K515A mutant 438309 4.1.1.90 0.043 - vitamin KH2 FLEEL, R359A/H360A/K361A mutant 438309 4.1.1.90 0.052 - reduced vitamin K1 pH 7.0 697705 4.1.1.90 0.053 - vitamin KH2 FLEEL, R406A/H408A mutant 438309 4.1.1.90 0.074 - precursor analog containing 29 amino acids of the propeptide region pH 7.0 697705 4.1.1.90 0.074 - vitamin KH2 FLEEL, FLAG-vitamin K-dependent gamma-glutamyl carboxylase 438309 4.1.1.90 0.075 - precursor analog containing 12 of the propeptide region pH 7.0 697705 4.1.1.90 0.097 - vitamin KH2 FLEEL, R234A/H235A mutant 438309 4.1.1.90 0.3 - CO2 pH 7.4 698695 4.1.1.90 0.42 - FLEEL pH 7.0 697705 4.1.1.90 0.54 - FLEEL wild type, pH 7.4, 20°C 698726 4.1.1.90 0.565 - conotoxin epsilon-TxIX pH 7.0 697705 4.1.1.90 0.78 - YVFLDHQDADANLILNRPKR FLAG-vitamin K-dependent gamma-glutamyl carboxylase, peptides comprising residue YVFLDHQDADANLILNRPKR concentration 1.6 microM 438309 4.1.1.90 0.78 - YVFLDHQDADANLILNRPKR FLAG-vitamin K-dependent gamma-glutamyl carboxylase, peptides comprising residue YVFLDHQDADANLILNRPKR concentration 160 microM 438309 4.1.1.90 0.91 - YVFLDHQDADANLILNRPKR FLAG-vitamin K-dependent gamma-glutamyl carboxylase, peptides comprising residue YVFLDHQDADANLILNRPKR concentration 0.16 microM 438309 4.1.1.90 0.92 - YVFLDHQDADANLILNRPKR R234A/H235A mutant, peptides comprising residue YVFLDHQDADANLILNRPKR concentration 160 microM 438309 4.1.1.90 1 - FLEEL wild type 438309 4.1.1.90 1.01 - YVFLDHQDADANLILNRPKR R406A/H408A mutant, proIX18 concentration 160 microM 438309 4.1.1.90 1.1 - FLEEL FLAG-vitamin K-dependent gamma-glutamyl carboxylase 438309 4.1.1.90 1.23 - YVFLDHQDADANLILNRPKR R406A/H408A mutant, peptides comprising residue YVFLDHQDADANLILNRPKR concentration 1.6 microM 438309 4.1.1.90 1.25 - YVFLDHQDADANLILNRPKR R234A/H235A mutant, peptides comprising residue YVFLDHQDADANLILNRPKR concentration 1.6 microM 438309 4.1.1.90 1.3 - FLEEL R234A/H235A mutant 438309 4.1.1.90 1.5 - FLEEL for wild type FLAG-vitamin K-dependent gamma-glutamyl carboxylase 438309 4.1.1.90 1.5 - FLEEL proPTl8 propeptide 696184 4.1.1.90 1.5 - FLEEL R359A/H360A/K361A mutant 438309 4.1.1.90 1.5 - FLEEL wild-type carboxylase in bovine liver microsomes 698697 4.1.1.90 1.54 - YVFLDHQDADANLILNRPKR R234A/H235A mutant, peptides comprising residue YVFLDHQDADANLILNRPKR concentration 0.16 microM 438309 4.1.1.90 1.6 - FLEEL pH 7.4 698695 4.1.1.90 1.6 - FLEEL proFIX19 propeptide 696184 4.1.1.90 1.6 - FLEEL R406A/H408A mutant 438309 4.1.1.90 1.6 - FLEEL recombinant His6-carboxylase present in Sf9 cell microsomes 698697 4.1.1.90 1.78 - YVFLDHQDADANLILNRPKR R406A/H408A mutant, peptides comprising residue YVFLDHQDADANLILNRPKR concentration 0.16 microM 438309 4.1.1.90 1.8 - FLEEL proFIX 19-6BPA propeptide 696184 4.1.1.90 1.9 - FLEEL proFIX19-16BPA propeptide 696184 4.1.1.90 1.9 - FLEEL R513A/K515A mutant 438309 4.1.1.90 2 - FLEEL proFIX19-13BPA propeptide 696184 4.1.1.90 2 - FLEEL proFIX19-7BPApropeptide 696184 4.1.1.90 2.01 - YVFLDHQDADANLILNRPKR FLAG-vitamin K-dependent gamma-glutamyl carboxylase, peptides comprising residue YVFLDHQDADANLILNRPKR concentration 0 microM 438309 4.1.1.90 2.03 - YVFLDHQDADANLILNRPKR R234A/H235A mutant, peptides comprising residue YVFLDHQDADANLILNRPKR concentration 0 microM 438309 4.1.1.90 2.06 - YVFLDHQDADANLILNRPKR R406A/H408A mutant, peptides comprising residue YVFLDHQDADANLILNRPKR concentration 0 microM 438309 4.1.1.90 6.49 - FLEEL L394R, pH 7.4, 20°C 698726 4.1.1.90 9 - FLEEL none propeptide 696184 4.1.1.90 14.8 - FLEEL Y395A, pH 7.4, 20°C 698726 4.1.1.90 24.3 - FLEEL W399A, pH 7.4, 20°C 698726