2.7.7.6 additional information - additional information - 643586 2.7.7.6 additional information - additional information relative KM-values for UTP derivatives 661927 2.7.7.6 0.000016 - promoter complex - 661148 2.7.7.6 0.0004 - dTTP - 663386 2.7.7.6 0.00072 - d(Tp4T) - 663386 2.7.7.6 0.00174 - d(Tp4G) - 663386 2.7.7.6 0.0018 - T10G2T2C2C - 661148 2.7.7.6 0.00211 - d(Ap4T) - 663386 2.7.7.6 0.00222 - d(Tp4C) - 663386 2.7.7.6 0.0095 - ATP pH 7.9, 37°C, wild-type enzyme 643584 2.7.7.6 0.0103 - rGTP pH 8.0, 37°C, rGTP as elongation substrate during dinucleotide synthesis, activation by Mn2+, wild-type enzyme 643574 2.7.7.6 0.0104 - rGTP pH 8.0, 37°C, rGTP as elongation substrate during dinucleotide synthesis, activation by Mg2+, mutant enzyme Y639F 643574 2.7.7.6 0.015 - dGTP pH 8.0, 37°C, dGTP as elongation substrate during dinucleotide synthesis, activation by Mg2+, mutant enzyme Y639F 643574 2.7.7.6 0.0153 - rGTP pH 8.0, 37°C, rGTP as elongation substrate during dinucleotide synthesis, activation by Mn2+, mutant enzyme Y639F 643574 2.7.7.6 0.016 - ATP pH 7.9, 37°C, mutant enzyme W422A 643584 2.7.7.6 0.0175 - rGTP pH 8.0, 37°C, rGTP as elongation substrate during dinucleotide synthesis, activation by Mg2+, wild-type enzyme 643574 2.7.7.6 0.018 - A10G2A2C2C - 661148 2.7.7.6 0.025 - dGTP pH 8.0, 37°C, dGTP as elongation substrate during dinucleotide synthesis, activation by Mg2+, mutant enzyme Y639F 643574 2.7.7.6 0.036 - ATP pH 7.9, 37°C, mutant enzyme Y427A 643584 2.7.7.6 0.036 - rUTP pH 8.0, 37°C, activation by Mn2+, wild-type enzyme 643574 2.7.7.6 0.041 - A9G3A2C2C - 661148 2.7.7.6 0.041 - rUTP pH 8.0, 37°C, activation by Mg2+, wild-type enzyme 643574 2.7.7.6 0.043 - G2CAC2C - 661148 2.7.7.6 0.067 - ATP pH 7.9, 37°C, mutant enzyme D421A 643584 2.7.7.6 0.079 0.107 UTP wild-type enzyme 643561 2.7.7.6 0.1 - GTP pH 7.9, 23°C 643571 2.7.7.6 0.137 - ATP pH 7.9, 37°C, mutant enzyme R423A 643584 2.7.7.6 0.14 0.142 ATP wild-type enzyme 643561 2.7.7.6 0.143 0.18 CTP wild-type enzyme 643561 2.7.7.6 0.21 - rGTP pH 8.0, 37°C, initiating nucleotide in rGrA synthesis, mutant enzyme S641A 643574 2.7.7.6 0.22 - rGTP pH 8.0, 37°C, initiating nucleotide in rGrA synthesis, mutant enzyme Y639F/S641A 643574 2.7.7.6 0.234 - GTP wild-type enzyme 643561 2.7.7.6 0.25 - rGTP pH 8.0, 37°C, initiating nucleotide in rGrA synthesis, wild-type enzyme 643574 2.7.7.6 0.282 - ATP pH 7.9, 37°C, mutant enzyme R425K 643584 2.7.7.6 0.32 - rGTP pH 8.0, 37°C, initiating nucleotide in rGrA synthesis, mutant enzyme Y639F 643574 2.7.7.6 0.384 - ATP pH 7.9, 37°C, mutant enzyme R425A 643584 2.7.7.6 0.387 - dGTP pH 8.0, 37°C, dGTP as elongation substrate during dinucleotide synthesis, activation with Mn2+ 643574 2.7.7.6 0.75 - dGTP pH 8.0, 37°C, initiating nucleotide in dGrA synthesis, mutant enzyme Y639F 643574 2.7.7.6 0.85 - dGTP pH 8.0, 37°C, dGTP as elongation substrate during dinucleotide synthesis, activation by Mg2+, wild-type enzyme 643574 2.7.7.6 0.88 - dGTP pH 8.0, 37°C, initiating nucleotide in rGrA synthesis, wild-type enzyme 643574 2.7.7.6 1.1 - dGTP pH 8.0, 37°C, initiating nucleotide in dGrA synthesis, mutant enzyme Y639F/S641A 643574 2.7.7.6 1.2 - dUTP pH 8.0, 37°C, activation by Mg2+, wild-type enzyme 643574 2.7.7.6 1.4 - dGTP pH 8.0, 37°C, initiating nucleotide in dGrA synthesis, wild-type enzyme 643574 2.7.7.6 1.7 - dUTP pH 8.0, 37°C, activation by Mg2+, wild-type enzymes 643574