2.7.11.11 additional information - additional information kinetics for cAMP binding to wild-type and mutant regulatory subunits RIIbeta, overview 662321 2.7.11.11 additional information - additional information kinetics for catalytic subunit Cgamma 663295 2.7.11.11 additional information - additional information kinetics of activation and autoinhibition, modeling, pre-steady-state kinetic methods, wild-type and mutant enzymes 490931 2.7.11.11 additional information - additional information kinetics of enzyme activity and activation 675598 2.7.11.11 additional information - additional information kinetics, random kinetic mechanism with kemptide as substrate, reaction kinetic can be influenced by the sort of substrate, pre-steady-state kinetics, slow structural changes during reaction 490935 2.7.11.11 additional information - additional information kinetics, thermodynamics, isozymes PKAmyt1 and PKAmyt2 660803 2.7.11.11 additional information - additional information PKA associates with substrates with a relatively low affinity 673866 2.7.11.11 additional information - additional information steady-state kinetics, second order rate constants, for the catalytic subunit 661314 2.7.11.11 0.0011 - N6-benzyl-ATP pH 7.0, 37°C, recombinant mutant M120G catalytic subunit 674804 2.7.11.11 0.0015 - N6-phenethyl-ATP pH 7.0, 37°C, recombinant mutant M120G catalytic subunit 674804 2.7.11.11 0.0019 - N-(8-([4-[3-(ethoxycarbonyl)-6,8,8-trimethyl-2-oxo-7,8-dihydro-2H-pyrano[3,2-g]quinolin-9(6H)-yl]butanoyl]amino)octanoyl)-GRTGRRFSYP-amide pH and temperature not specified in the publication 721744 2.7.11.11 0.0022 - N-(8-([[7-(diethylamino)-2-oxo-2H-chromen-3-yl]carbonyl]amino)octanoyl)-GRTGRRFSYP-amide pH and temperature not specified in the publication 721744 2.7.11.11 0.0062 - N-(8-[[(11-oxo-2,3,6,7-tetrahydro-1H,5H,11H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-10-yl)carbonyl]amino]octanoyl)-GRTGRRFSYP-amide pH and temperature not specified in the publication 721744 2.7.11.11 0.00974 - Kemptide 25°C, pH 7.4, wild-type enzyme 761094 2.7.11.11 0.0125 - Kemptide C-subunit isoform C5, in 50 mM Tris-HCl (pH 7.0), 1 mM dithiothreitol, 5 mM MgCl2, 0.2 mM ATP, at 25°C 692313 2.7.11.11 0.0125 - Kemptide C-subunit isoform C6, in 50 mM Tris-HCl (pH 7.0), 1 mM dithiothreitol, 5 mM MgCl2, 0.2 mM ATP, at 25°C 692313 2.7.11.11 0.0125 - Kemptide pH 7.0, 30°C, recombinant catalytic subunit Cgamma 663295 2.7.11.11 0.0147 - Kemptide C-subunit isoform C3, in 50 mM Tris-HCl (pH 7.0), 1 mM dithiothreitol, 5 mM MgCl2, 0.2 mM ATP, at 25°C 692313 2.7.11.11 0.0158 - Kemptide C-subunit isoform C1, in 50 mM Tris-HCl (pH 7.0), 1 mM dithiothreitol, 5 mM MgCl2, 0.2 mM ATP, at 25°C 692313 2.7.11.11 0.0169 - ATP 25°C, pH 7.4, wild-type enzyme 761094 2.7.11.11 0.0174 - ATP pH 7.0, 37°C, recombinant wild-type catalytic subunit 674804 2.7.11.11 0.0186 - Kemptide C-subunit isoform C4, in 50 mM Tris-HCl (pH 7.0), 1 mM dithiothreitol, 5 mM MgCl2, 0.2 mM ATP, at 25°C 692313 2.7.11.11 0.019 - ATP pH 7.0, temperature not specified in the publication, wild-type enzyme 722989 2.7.11.11 0.021 - RRASVA pH 7.5, 25°C, catalytic subunit 661266 2.7.11.11 0.023 - ATP pH 7.0, temperature not specified in the publication, myristoylated wild-type enzyme and enzyme mutant K7C 722989 2.7.11.11 0.023 - Leu-Arg-Arg-Ala-Ser-Leu-Gly pH 7.0, temperature not specified in the publication, myristoylated wild-type enzyme 722989 2.7.11.11 0.0247 - Kemptide C-subunit isoform C2, in 50 mM Tris-HCl (pH 7.0), 1 mM dithiothreitol, 5 mM MgCl2, 0.2 mM ATP, at 25°C 692313 2.7.11.11 0.0253 - RFARKGSLREKNV pH 7.0, 30°C, recombinant catalytic subunit Cgamma 663295 2.7.11.11 0.027 - Leu-Arg-Arg-Ala-Ser-Leu-Gly pH 7.0, temperature not specified in the publication, enzyme mutant K7C 722989 2.7.11.11 0.027 - peptide RRYSV wild type enzyme, at pH 7.0 and 25°C 739590 2.7.11.11 0.0276 - ATP 25°C, pH 7.4, mutant enzyme L205R 761094 2.7.11.11 0.029 - Leu-Arg-Arg-Ala-Ser-Leu-Gly pH 7.0, temperature not specified in the publication, wild-type enzyme 722989 2.7.11.11 0.029 - peptide RRYSV mutant enzyme N326C, at pH 7.0 and 25°C 739590 2.7.11.11 0.0305 - ATP pH 7.0, 37°C, recombinant mutant M120G catalytic subunit 674804 2.7.11.11 0.031 - Kemptide pH 7.0, 22°C, catalytic subunit 661884 2.7.11.11 0.032 - ATP pH 7.0, temperature not specified in the publication, myristoylated enzyme mutant K7C 722989 2.7.11.11 0.0333 - RKRSRAE pH 7.0, 30°C, recombinant catalytic subunit Cgamma 663295 2.7.11.11 0.0333 - RKRSRKE pH 7.0, 30°C, recombinant catalytic subunit Cgamma 663295 2.7.11.11 0.038 - Kemptide pH 7.0, 30°C, recombinant catalytic subunit Calpha 663295 2.7.11.11 0.039 - ATP ATP in form of MgATP2- 661884 2.7.11.11 0.039 - ATP pH 7.0, 22°C, catalytic subunit 661884 2.7.11.11 0.043 - Leu-Arg-Arg-Ala-Ser-Leu-Gly pH 7.0, temperature not specified in the publication, myristoylated enzyme mutant K7C 722989 2.7.11.11 0.05 - RFARKGSLREKNV pH 7.0, 30°C, recombinant catalytic subunit Calpha 663295 2.7.11.11 0.0503 - RRLSSLRA pH 7.0, 30°C, recombinant catalytic subunit Cgamma 663295 2.7.11.11 0.0609 - Kemptide 25°C, pH 7.4, mutant enzyme L205R 761094 2.7.11.11 0.1 - N6-benzyl-ATP above, pH 7.0, 37°C, recombinant wild-type catalytic subunit 674804 2.7.11.11 0.293 - RKRSRAE pH 7.0, 30°C, recombinant catalytic subunit Calpha 663295 2.7.11.11 0.338 - RRLSSLRA pH 7.0, 30°C, recombinant catalytic subunit Calpha 663295 2.7.11.11 0.5 - RKRSRKE pH 7.0, 30°C, recombinant catalytic subunit Calpha 663295 2.7.11.11 0.73 - histone pH 7.0, 22°C, catalytic subunit 661884