2.7.1.147 5-iodotubercidin - 36413 2.7.1.147 8-bromoadenosine phosphate competitive. The binding of the inhibitor induces major conformational changes 256648 2.7.1.147 8-bromoadenosine phosphate competitive 256648 2.7.1.147 ADP - 13 2.7.1.147 ADP strong inhibition effect in the reverse glucokinase reaction 13 2.7.1.147 ADP substrate inhibition 13 2.7.1.147 AMP strong competitive inhibition 30 2.7.1.147 AMP strong substrate inhibition effect in the reverse glucokinase reaction; substrate inhibition effect (Ki of 0.4 mM at 10 mM of glucose 6-phosphate). At a glucose 6-phosphate concentration of 0.5 mM, a sigmoidal behavior is observed, along with an even more pronounced inhibition 30 2.7.1.147 AMP - 30 2.7.1.147 D-fructose - 117