5.4.99.18	additional information	high-throughput screening of compounds binding to Bacillus anthracis PurE. A a low ionic strength buffer condition is used to accentuate the thermal shift stabilization induced by compound binding to Bacillus anthracis PurE. Computational ligand docking to the active site. Determination of inhibitory compounds for inhibition of BaPurE activity and for cytotoxicity against Bacillus anthracis (DELTAANR strain), Escherichia coli (BW25113 strain, wild-type and DELTATolC), Francisella tularensis, Staphylococcus aureus (both methicillin susceptible and methicillin-resistant strains) and Yersinia pestis. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values, overview	2	
5.4.99.18	Ciprofloxacin	-	1229	
5.4.99.18	3,4-dihydroxybenzoic acid	a scaffold hit from library screening	1781	
5.4.99.18	linezolid	-	18943	
5.4.99.18	4-Nitro-5-aminoimidazole ribonucleotide	NAIR	20632	
5.4.99.18	5-fluoro-1H-indole-2-carboxylic acid	a scaffold hit from library screening	117342	
5.4.99.18	isoquinolin-1-amine	a scaffold hit from library screening	212860	
5.4.99.18	(2-bromo-5-ethoxy-4-methoxyphenyl)methanol	-	226256	
5.4.99.18	(2-ethoxyphenyl)(morpholino)methanethione	-	226257	
5.4.99.18	(5-(2-chlorophenyl)isoxazol-3-yl)methanamine	-	226400