4.4.1.20 additional information cell treatment with ERK 1/2 specific inhibitor 1,4-diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene (U0126) blocks LTC4S expression, pyrrolidine dithiocarbamate inhibits reactive oxygen species generation and NF-?B activation, which in turn blocks LTC4S expression 2 4.4.1.20 Co2+ - 23 4.4.1.20 NaCl 0.5 mM, about 25% inhibition 42 4.4.1.20 N-ethylmaleimide inhibits the recombinant enzyme 49 4.4.1.20 KCl 0.5 mM, about 25% inhibition 79 4.4.1.20 NEM IC50: 0.02 mM 89 4.4.1.20 NEM IC50: 0.018 mM 89 4.4.1.20 NEM - 89 4.4.1.20 bovine serum albumin 5 mg, 45% inhibition 274 4.4.1.20 indomethacin IC50: 1.0 mM 546