4.1.99.2	1,2-dihydroxybenzene	cleavage of Tyr	10458	
4.1.99.2	1,3-dihydroxybenzene	cleavage of Tyr	8988	
4.1.99.2	1-amino-2-(4-hydroxyphenyl)-ethyl phosphinic acid	-	22585	
4.1.99.2	1-amino-2-(4-hydroxyphenyl)-ethyl phosphonic acid	-	54498	
4.1.99.2	2-Aminophenol	cleavage of Tyr	1910	
4.1.99.2	2-aza-L-tyrosine	competitive	33837	
4.1.99.2	2-bromophenol	cleavage of Tyr	10828	
4.1.99.2	2-chlorophenol	cleavage of Tyr	2929	
4.1.99.2	2-Fluorophenol	cleavage of Tyr	5470	
4.1.99.2	2-iodophenol	cleavage of Tyr	45115	
4.1.99.2	2-methylphenol	cleavage of Tyr	7994	
4.1.99.2	3,4-dihydroxyphenyl-L-alanine	inactivated by a Pictet-Spengler reaction between the cofactor and 3,4-dihydroxyphenyl-L-alanine, on treatment with excess pyridoxal-5'-phosphate the inactivated enzymes recovers over 80% of the original activity	7593	
4.1.99.2	3-Aminophenol	cleavage of Tyr	6439	
4.1.99.2	3-aza-L-tyrosine	competitive	118334	
4.1.99.2	3-bromophenol	cleavage of Tyr	16032	
4.1.99.2	3-chlorophenol	cleavage of Tyr	2259	
4.1.99.2	3-Fluorophenol	cleavage of Tyr	4479	
4.1.99.2	3-iodophenol	cleavage of Tyr	45164	
4.1.99.2	3-methylphenol	cleavage of Tyr	6037	
4.1.99.2	4-Aminophenol	cleavage of Tyr	3441	
4.1.99.2	4-hydroxyphenylpropionate	competitive inhibitor, addition of 4-hydroxypyridin in the reaction results in decay of the quinonoid-aldimine spectrum with rate constant of 1.4/s and formation of an intermediate absorbing at 338 nm, assigned to an aminoacrylate intermediate	227777	
4.1.99.2	4-hydroxypyridine	cleavage of Tyr	10837	
4.1.99.2	D-Ala	competitive	291	
4.1.99.2	L-Ala	competitive	251	
4.1.99.2	L-Ala	-	251	
4.1.99.2	L-Ala	inhibits pyruvate formation from L-Tyr	251	
4.1.99.2	L-Asp	-	294	
4.1.99.2	L-bishomotyrosine	-	227243	
4.1.99.2	L-Glu	-	202	
4.1.99.2	L-homoserine	-	345	
4.1.99.2	L-homotyrosine	-	227244	
4.1.99.2	L-m-Tyr	competitive	10868	
4.1.99.2	L-Met	-	468	
4.1.99.2	L-methionine	inhibition of alpha,beta-elimination reaction	88	
4.1.99.2	L-Phe	competitive	203	
4.1.99.2	L-Phe	-	203	
4.1.99.2	L-Phe	inhibits pyruvate formation from L-Tyr	203	
4.1.99.2	L-phenylalanine	-	104	
4.1.99.2	L-phenylalanine	inhibition of alpha,beta-elimination reaction	104	
4.1.99.2	L-tryptophan	-	119	
4.1.99.2	L-tyrosine	-	109	
4.1.99.2	additional information	-	2	
4.1.99.2	additional information	inhibition of tyrosine phenol-lyase by tyrosine homologues and their O-methyl derivatives, overview. Synthesis, and steady-state and pre-steady-state kinetic evaluations of L-homotyrosine and L-bishomotyrosine as possible mechanism-based inhibitors for TPL	2	
4.1.99.2	additional information	The mutant S51A also shows intermediate formation with L-Met and L-Phe. Influence of replacement of Ser51 by Ala on the kinetic parameters of TPL reactions with L-phenylalanine and L-methionine, kinetics and structures, overview	2	
4.1.99.2	Na+	-	59	
4.1.99.2	O-methyl-L-bishomotyrosine	-	227469	
4.1.99.2	O-methyl-L-homotyrosine	-	227470	
4.1.99.2	per(2,3,6-tri-O-methyl)-alpha-cyclodextrin	non-competitive	129844	
4.1.99.2	per(2,3,6-tri-O-methyl)-beta-cyclodextrin	non-competitive	129845	
4.1.99.2	per(2,3,6-tri-O-methyl)-gamma-cyclodextrin	non-competitive	129846	
4.1.99.2	phenol	cleavage of Tyr	249	
4.1.99.2	phenol	cleavage of Tyr; mixed type inhibion	249	
4.1.99.2	phenol	100 mM and above	249	
4.1.99.2	phenol	In presence of 1 mM, only 23% of the original activity remained. The presence of phenol seriously affects its own production, through the inhibition of TPL	249	
4.1.99.2	pyrocatechol	inhibits pyruvate formation from L-Tyr, mixed type	4047