3.5.1.19	2,2'-dipyridyl	Mg2+ reverses inhibition	375	
3.5.1.19	2-chloropyridine-3-carbaldehyde	-	28764	
3.5.1.19	2-mercaptoethanol	-	63	
3.5.1.19	3-(3-pyridyl)-1-propanol	moderate	104761	
3.5.1.19	3-acetylpyridine	moderate	3783	
3.5.1.19	3-acetylpyridine	competitive	3783	
3.5.1.19	3-acetylpyridine	-	3783	
3.5.1.19	3-acetylpyridine	competitive inhibition	3783	
3.5.1.19	3-aminomethylpyridine	potent	8380	
3.5.1.19	3-chloropyridine	moderate	48594	
3.5.1.19	3-Cyanopyridine	potent	1784	
3.5.1.19	3-Cyanopyridine	-	1784	
3.5.1.19	3-hydroxypyridine	-	13128	
3.5.1.19	3-indolepropionic acid	inhibits amidase and esterase activity	21474	
3.5.1.19	3-pyridine carboxaldehyde	competitive inhibitor	31955	
3.5.1.19	3-Pyridineacetonitrile	moderate	43363	
3.5.1.19	3-pyridinealdoxime	potent	104887	
3.5.1.19	3-Pyridinecarboxaldehyde	potent	3056	
3.5.1.19	3-Pyridylcarbinol	potent	12358	
3.5.1.19	4-aminonicotinamide	potent	104968	
3.5.1.19	4-methoxylnicotinaldehyde	weak inhibitor	7934	
3.5.1.19	5-bromo-nicotinaldehyde	-	247515	
3.5.1.19	5-bromonicotinaldehyde	competitive inhibition	206443	
3.5.1.19	5-bromonicotinaldehyde	-	206443	
3.5.1.19	5-bromopyridine-3-carbaldehyde	potent inhibitor	28766	
3.5.1.19	5-methoxynicotinaldehyde	competitive inhibitor	169819	
3.5.1.19	5-methoxypyridine-3-carbaldehyde	potent inhibitor	7060	
3.5.1.19	5-methylnicotinaldehyde	-	15258	
3.5.1.19	5-Methylnicotinamide	competitive	7130	
3.5.1.19	5-Methylnicotinamide	moderate	7130	
3.5.1.19	5-methylpyridine-3-carbaldehyde	potent inhibitor	15259	
3.5.1.19	6-fluoropyridine-3-carbaldehyde	-	28765	
3.5.1.19	8-hydroxyquinoline	-	321	
3.5.1.19	Ag+	-	75	
3.5.1.19	benzaldehyde	competitive inhibition	146	
3.5.1.19	benzoic acid	inhibits amidase and esterase activity	498	
3.5.1.19	Carbobenzoxyamido-2-phenyl-ethyl-chloromethyl-ketone	-	97805	
3.5.1.19	Cu2+	CuSO4	19	
3.5.1.19	Cu2+	-	19	
3.5.1.19	CuCl2	-	347	
3.5.1.19	Cys	-	553	
3.5.1.19	diisopropylfluorophosphate	-	299	
3.5.1.19	dithiothreitol	-	45	
3.5.1.19	EDTA	-	21	
3.5.1.19	EDTA	2 mM, no effect	21	
3.5.1.19	EDTA	0.02 mM, 46% inhibition	21	
3.5.1.19	EDTA	10 mM, 57% loss of activity	21	
3.5.1.19	Fe2+	-	25	
3.5.1.19	Fe2+	FeCl2	25	
3.5.1.19	Fe3+	1 mM, 94% inhibition	70	
3.5.1.19	guanidinium hydrochloride	3.4 M, complete inhibition	3124	
3.5.1.19	Hg2+	-	33	
3.5.1.19	HgCl2	-	110	
3.5.1.19	Hydrocinnamic acid	inhibits amidase and esterase activity	12555	
3.5.1.19	iodoacetamide	reversible, competitive inhibitor	67	
3.5.1.19	isoniazid	moderate	851	
3.5.1.19	L-thyroxine	-	1380	
3.5.1.19	additional information	pyridine nitrogen and the carbonyl carbon of nicotinamide are involved in substrate-enzyme binding, and the enzyme exhibits steric hindrance in binding nicotinamide analogues with substituents at the 1-position, 5-position, and 6-positions of the pyridine ring	2	
3.5.1.19	additional information	enzyme is not a subject to feedback inhibition	2	
3.5.1.19	additional information	not inhibited by 3-hydroxypyridine	2	
3.5.1.19	additional information	not inhibited by nicotinic acid	2	
3.5.1.19	additional information	not inhibited by 3-hydroxypyridine and 2-chloropyridine-3-carbaldehyde	2	
3.5.1.19	additional information	not inhibited by 3-hydroxypyridine and 6-fluoropyridine-3-carbaldehyde	2	
3.5.1.19	additional information	not inhibited by 10 mM EDTA	2	
3.5.1.19	N,N'-diethylnicotinamide	competitive	109203	
3.5.1.19	N-ethylmaleimide	-	49	
3.5.1.19	N2-ethylnicotinamide	competitive	106791	
3.5.1.19	N2-methylnicotinamide	competitive	106792	
3.5.1.19	NaCl	500 mM, 12% inhibition	42	
3.5.1.19	NaCl	50 mM, 12% inhibition	42	
3.5.1.19	NAD+	competitive with respect to nicotinamide	7	
3.5.1.19	NiCl2	-	741	
3.5.1.19	nicotinal hydroxamic acid	moderate	106845	
3.5.1.19	nicotinaldehyde	-	4650	
3.5.1.19	nicotinaldehyde	potent competitive inhibitor	4650	
3.5.1.19	nicotinaldehyde	competitive inhibitor	4650	
3.5.1.19	nicotinaldehyde	most potent inhibitor	4650	
3.5.1.19	nicotinaldehyde	competitive inhibition	4650	
3.5.1.19	nicotinamide	inhibits esterolysis of p-nitrophenyl acetate	267	
3.5.1.19	nicotinamide analogs	analogs with a trivalent nitrogen, competitive inhibition	106847	
3.5.1.19	nicotinic acid	inhibits amidase and esterase activity	1282	
3.5.1.19	nicotinic acid	-	1282	
3.5.1.19	nicotinic acid	competitive inhibition	1282	
3.5.1.19	nicotinic acid hydrazide	potent	9552	
3.5.1.19	nicotinic acid hydrazide	competitive	9552	
3.5.1.19	nipecotamide	moderate	106849	
3.5.1.19	o-bromobenzamide	moderate	106903	
3.5.1.19	p-nitrophenol	inhibits amidase and esterase activity	151	
3.5.1.19	PCMB	-	78	
3.5.1.19	Pyrazinamide	moderate	3666	
3.5.1.19	Pyrazinamide	the natural resistance of Mycobacterium kansasii to pyrazinamide is due to a deficient pyrazinamidase activity of nicotinamidase	3666	
3.5.1.19	pyrazinecarbonitrile	irreversible inactivator	169818	
3.5.1.19	pyrazinoic acid	competitive inhibition	21690	
3.5.1.19	pyridine-3-carbonitrile	reversible, competitive inhibitor	88024	
3.5.1.19	Sodium diethyl dithiocarbamate	-	6591	
3.5.1.19	sulfhydryl reagents	-	978	
3.5.1.19	Thionicotinamide	moderate	8199	
3.5.1.19	Triton X-100	0.1%, 24% inhibition	61	
3.5.1.19	Urea	8 M, complete inhibition	116	
3.5.1.19	Urea	1 M, 20% inhibition	116	
3.5.1.19	Zn2+	ZnCl2	14	
3.5.1.19	Zn2+	-	14	
3.5.1.19	Zn2+	5 mM, complete inactivation	14	
3.5.1.19	Zn2+	5 mM, complete inhibition	14	
3.5.1.19	ZnCl2	-	271