3.4.21.95 Acetylsalicylic acid aspirin, reduces markedly platelet aggregating effect induced by VLCII, less effective compared to clopidogrel 2261 3.4.21.95 ADP reduces slightly platelet aggregating effect induced by VLCII 13 3.4.21.95 clopidogrel P2Y12 adenosine diphosphate (ADP) receptor inhibitor, reduces markedly platelet aggregating effect induced by VLCII 161060 3.4.21.95 D-Phe-Pro-Arg-chloromethylketone - 22537 3.4.21.95 diisopropyl fluorophosphate - 244 3.4.21.95 diisopropylfluorophosphate - 299 3.4.21.95 heparin at high concentrations, more than 100 units 227 3.4.21.95 additional information no inhibition of the proteolytic activity of VLCII by EDTA and 1,10-phenanthroline, poor inhibition by EGTA. VLCII activity on platelet aggregation is tested after treatment with acetylsalicylic acid (aspirin) irreversible inhibitor of cyclooxygenase-1 (COX-1) and clopidogrel (plavix) antagonist of P2Y12 receptor 2 3.4.21.95 pefabloc 4-(2-aminoethyl)-benzenesulfonyl fluoride 2236 3.4.21.95 PMSF 82% inhibition 248 3.4.21.95 PMSF - 248