3.1.3.56 2,3-bisphosphoglycerate competitive with D-myo-inositol 1,4,5-trisphosphate 1251 3.1.3.56 2,3-bisphosphoglycerate - 1251 3.1.3.56 2,3-dihydroxybenzene 1,4-bisphosphate - 36982 3.1.3.56 3-benzyloxybenzene 1,2,4-trisphosphate - 74904 3.1.3.56 3-hydroxybenzene 1,2,4-trisphosphate - 18530 3.1.3.56 ADP - 13 3.1.3.56 ammonium phosphate - 115256 3.1.3.56 AMP slight inhibition 30 3.1.3.56 ATP - 4 3.1.3.56 benzene 1,2,3,4-tetrakisphosphate - 14424 3.1.3.56 benzene 1,2,3,5-tetrakisphosphate - 14425 3.1.3.56 benzene 1,2,3-trisphosphate - 14422 3.1.3.56 benzene 1,2,4,5-tetrakisphosphate - 14426 3.1.3.56 benzene 1,2,4-trisphosphate - 10050 3.1.3.56 benzene 1,2-bisphosphate - 74903 3.1.3.56 benzene 1,3,5-trisphosphate - 14423 3.1.3.56 biphenyl 2,3',4,5',6-pentakisphosphate - 14427 3.1.3.56 Ca2+ above 0.001 mM 15 3.1.3.56 Ca2+ competitive to Mg2+ 15 3.1.3.56 CdCl2 - 906 3.1.3.56 Cu2+ - 19 3.1.3.56 D-6-deoxy-myo-inositol 1,3,4,5-tetrakisphosphate - 129717 3.1.3.56 D-fructose 1,6-bisphosphate - 106 3.1.3.56 D-fructose 2,6-bisphosphate - 714 3.1.3.56 D-Glucose 1,6-bisphosphate - 1642 3.1.3.56 D-glucose 6-phosphate slight inhibition 105 3.1.3.56 D-glucose 6-phosphate - 105 3.1.3.56 Disulfiram - 986 3.1.3.56 EDTA - 21 3.1.3.56 EDTA no activity in presence of 1 mM EDTA 21 3.1.3.56 Glycerophosphoinositol 4,5-bisphosphate competitive with D-myo-inositol 1,4,5-trisphosphate 44181 3.1.3.56 Glycerophosphoinositol 4-phosphate - 30054 3.1.3.56 Inositol 1,3,4,5,6-pentakisphosphate - 4258 3.1.3.56 Inositol 1,3,4,5-tetrakisphosphate competitive with D-myo-inositol 1,4,5-trisphosphate 4259 3.1.3.56 Inositol 1,3,4,5-tetrakisphosphate - 4259 3.1.3.56 inositol 1,4-bisphosphate - 4020 3.1.3.56 Inositol hexakisphosphate competitive 2024 3.1.3.56 L-chiro-Inositol 1,4,6-trisphosphorothioate very potent inhibitor 30117 3.1.3.56 L-chiro-Inositol 2,3,5-trisphosphorothioate very potent inhibitor 30118 3.1.3.56 L-myo-inositol 1,3,5-trisphosphorothioate very potent inhibitor 33457 3.1.3.56 L-myo-inositol 1,4,5-trisphosphorothioate very potent inhibitor 33458 3.1.3.56 Mg2+ above 12 mM 6 3.1.3.56 Mg2+ above 0.5 mM 6 3.1.3.56 Mg2+ above 3 mM 6 3.1.3.56 additional information inositol 1,4-bisphosphate does not inhibit enzyme activity 2 3.1.3.56 N-ethylmaleimide - 49 3.1.3.56 p-hydroxymercuribenzoate - 98 3.1.3.56 Phenylglyoxal Arg-343 and Arg-350 were found to be covalently modified; irreversible, substrates and 2,3-bisphosphoglycerate protect against inactivation 301 3.1.3.56 phosphate - 16 3.1.3.56 protein PRIP-1 binding to PRIP-1, a Ins(1,4,5)P3-binding protein, inhibits the enzyme in vitro, in vivo binding of Ins(1,4,5)P3 to PRIP-1 prevents it from being hydrolyzed by the enzyme, PRIP-1 has a domain organization similar to phospholipase C-delta1, interaction analysis, overview 129716 3.1.3.56 SDS no activity with 0.1% 124 3.1.3.56 thimerosal - 2762 3.1.3.56 Triton X-100 20% of activity remaining with 1% 61 3.1.3.56 vanadate 30% inhibition at 1 mM 233