2.7.4.14 5-Br-uracil vinylphosphonate - 36432 2.7.4.14 5-Cl-uracil vinylphosphonate - 36433 2.7.4.14 5-F-Phe-uracil vinylphosphonate - 62642 2.7.4.14 5-Phe-S-uracil vinylphosphonate - 24451 2.7.4.14 5-Phe-uracil vinylphosphonate - 135614 2.7.4.14 ADP - 13 2.7.4.14 CDP competitive 212 2.7.4.14 CDP competitive withCMP 212 2.7.4.14 CMP above 0.13 mM, substrate inhibition 100 2.7.4.14 CMP competitive inhibition of UMP phosphorylation 100 2.7.4.14 CMP substrate inhibition above 0.2 mM 100 2.7.4.14 CTP inhibits reaction with ATP and UMP, CMP or dCMP 60 2.7.4.14 CuSO4 0.25 mM, 96% inhibition of enzyme form UMPK1 and 92% inhibition of enzyme form UMPK2 263 2.7.4.14 dADP - 731 2.7.4.14 dCDP - 1124 2.7.4.14 dCMP competitive inhibition of UMP phosphorylation 450 2.7.4.14 dCTP inhibits reaction with ATP and UMP, CMP or dCMP 179 2.7.4.14 dTDP - 542 2.7.4.14 DTNB 0.009 mM, 50% inhibition 554 2.7.4.14 F- complete inhibition at 25 mM 174 2.7.4.14 HgCl2 0.25 mM, complete inhibition of enzyme form UMPK1 and UMPK2 110 2.7.4.14 HgCl2 0.1 mM, 88% inhibition 110 2.7.4.14 iodoacetamide - 67 2.7.4.14 iodoacetate 0.05 mM, 50% inhibition 93 2.7.4.14 L-CMP excess of L-CMP 24450 2.7.4.14 lead nitrate 0.25 mM, 52% inhibition of enzyme form UMPK1 and 40% inhibition of enzyme form UMPK2 22325 2.7.4.14 MgATP2- competitive with UMP 108 2.7.4.14 additional information no substrate inhibition with 3 mM dCMP and 1 mM UMP 2 2.7.4.14 NaClO 250 mM 116170 2.7.4.14 NaSCN 250 mM 10731 2.7.4.14 NEM 0.035 mM, 50% inhibition 89 2.7.4.14 NEM 1.0 mM; 41% inhibition 89 2.7.4.14 p-hydroxymercuribenzoate 0.02 mM, 50% inhibition 98 2.7.4.14 p-Hydroxymercuriphenyl sulfonate 0.02 mM, 50% inhibition 15904 2.7.4.14 P1,P5-di(adenosine-5')pentaphosphate - 2151 2.7.4.14 PCMB 0.1 mM, 69% loss of activity 78 2.7.4.14 TTP inhibits reaction with ATP and UMP, CMP or dCMP 523 2.7.4.14 UDP product inhibition 26 2.7.4.14 UMP substrate inhibition above 0.2 mM 133 2.7.4.14 uracil vinylphosphonate - 36431 2.7.4.14 UTP inhibits reaction with ATP and UMP, CMP or dCMP 65 2.7.4.14 ZnCl2 0.25 mM, 55% inhibition of enzyme form UMPK1 and 30% inhibition of enzyme form UMPK2 271