2.7.1.49 (6R)-6-[(2E)-4-oxo-6-phenylhex-2-en-1-yl]-5,6-dihydro-2H-pyran-2-one lactone isolated from Cryptocarya rugulosa, covalent inhibition 28859 2.7.1.49 (6R)-6-[(2E)-6-(4-ethynylphenyl)-4-oxohex-2-en-1-yl]-5,6-dihydro-2H-pyran-2-one derivative of a lactone isolated from Cryptocarya rugulosa, covalent inhibition 28860 2.7.1.49 (6S)-6-[(2E)-6-(4-ethynylphenyl)-4-oxohex-2-en-1-yl]tetrahydro-2H-pyran-2-one derivative of a lactone isolated from Cryptocarya rugulosa, covalent inhibition 28861 2.7.1.49 2-methyl-4-amino-5-hydroxymethylpyrimidine competitive inhibition 7509 2.7.1.49 additional information stable to treatment with p-hydroxymercuribenzoate 2 2.7.1.49 pyridoxine inhibits competitively the phosphorylation of 2-methyl-4-amino-5-hydroxymethylpyrimidine 1051 2.7.1.49 rugulactone selectively modifies the enzyme not at the active site cysteine, but on a remote cysteine residue 213282