2.7.1.147	5-iodotubercidin	-	36413	
2.7.1.147	8-bromoadenosine phosphate	competitive. The binding of the inhibitor induces major conformational changes	256648	
2.7.1.147	8-bromoadenosine phosphate	competitive	256648	
2.7.1.147	ADP	-	13	
2.7.1.147	ADP	strong inhibition effect in the reverse glucokinase reaction	13	
2.7.1.147	ADP	substrate inhibition	13	
2.7.1.147	AMP	strong competitive inhibition	30	
2.7.1.147	AMP	strong substrate inhibition effect in the reverse glucokinase reaction; substrate inhibition effect (Ki of 0.4 mM at 10 mM of glucose 6-phosphate). At a glucose 6-phosphate concentration of 0.5 mM, a sigmoidal behavior is observed, along with an even more pronounced inhibition	30	
2.7.1.147	AMP	-	30	
2.7.1.147	D-fructose	-	117	
2.7.1.147	D-fructose 6-phosphate	competitive inhibition of D-fructose 6-phosphate when glucose is used as the variable substrate; strong inhibition of glucokinase activity, competitive inhibion versus D-glucose as variable substrate	87	
2.7.1.147	D-glucosamine	-	699	
2.7.1.147	D-glucose	substrate inhibition above 200 mM. At 10 mM 20% inhibition of phosphofructokinase activity	35	
2.7.1.147	D-glucose	-	35	
2.7.1.147	EDTA	50 mM, complete inhibition; complete loss of activity; completely abolishes activity	21	
2.7.1.147	KCl	inhibition by KCl is only partially prevented by glycine betaine	79	
2.7.1.147	KCl	activates at up to 0.5 M, inhibitory above about 1.0 M, inhibition by KCl is prevented by glycine betaine	79	
2.7.1.147	Mg2+	excess Mg2+ is inhibitory, 55% inhibition at 55 mM, 41% at 15 mM, and 22% at 10 mM	6	
2.7.1.147	additional information	no inhibition by D-glucose 6-phosphate, no or nearly no inhibition by L-glucose, glucose 1-phosphate, fructose 1-phosphate, 2,3-bisphosphoglycerate, succinate, proline, N-acetylglucosamine, diphosphate, mannose, galactose, fructose, ribose, NH4Cl, IMP, glucosamine, inositol, phosphocreatine, ATP, GTP, CTP, GDP, UTP, TTP, NADP+, oxaloacetate, TDP, CDP, UDP, palmitate, D-glucose 1,6-bisphosphate, and several other compounds, overview	2	
2.7.1.147	additional information	enzyme TlGK is not significantly inhibited by D-fructose 6-phosphate	2	
2.7.1.147	NaCl	84% of maximal activity at 0.5 M, 48% of maximal activity at 1 M	42	
2.7.1.147	NaCl	moderate inhibition by 300 mM NaCl or higher concentration	42