1.5.1.6	5,10-dideazatetrahydrofolate	0.4 mM, 98% inhibition, folate analog	4946	
1.5.1.6	5-formyltetrahydrofolate	covalent attachment completely inhibits	1611	
1.5.1.6	chymotrypsin	cleavage between the two domains, inactivates 10-formyltetrahydrofolate dehydrogenase but not hydrolase and aldehyde dehydrogenase activity	2434	
1.5.1.6	hydroxylamine	0.1 M, strong inhibition	85	
1.5.1.6	iodoacetamide	inhibition reversed by 2-mercaptoethanol	67	
1.5.1.6	additional information	-	2	
1.5.1.6	additional information	not inhibited by (+)-10-formyltetrahydrofolate, 5-formyltetrahydrofolate, 5-methyltetrahydrofolate, folate, aminopterin, tetrahydroaminopterin	2	
1.5.1.6	additional information	not inhibited by NADPH	2	
1.5.1.6	additional information	not inhibited by the folate analog N-[4-[[3-(2,4-diamino-1,6-dihydro-6-oxo-5-pyrimidinyl)propyl]amino]-benzoyl]-L-glutamate	2	
1.5.1.6	additional information	recombinant FDH is not inhibited by sodium azide	2	
1.5.1.6	N-ethylmaleimide	1 mM or 10 mM, complete inhibition	49	
1.5.1.6	p-chloromercuribenzoate	inhibition reversed by 2-mercaptoethanol	43	
1.5.1.6	propanal	FDH activity decreases with increasing concentrations, competes with 10-formyltetrahydrofolate for NADP+-dependent oxidation	328	
1.5.1.6	Subtilisin	cleavage between the two domains, inactivates 10-formyltetrahydrofolate dehydrogenase but not hydrolase and aldehyde dehydrogenase activity	7365	
1.5.1.6	tetrahydrofolate	-	207	
1.5.1.6	tetrahydrofolate	strong product inhibition by both isomers	207	
1.5.1.6	tetrahydrofolate	very strong product inhibition	207	
1.5.1.6	tetrahydrofolate	competitive to 10-formyltetrahydrofolate and non-competitive to NADP+; very strong product inhibition	207	
1.5.1.6	tetrahydrofolate	potent, competitive product inhibitor	207	
1.5.1.6	tetrahydropteroylhexaglutamate	1 mol per mol of tetrameric protein, potent product inhibitor: 0.0003 mM, 90% inhibition	20831	
1.5.1.6	Tetrahydropteroylpentaglutamate	strong product inhibition	5221	
1.5.1.6	tetrahydropteroylpolyglutamate	inhibition increases with increasing length of polyglutamyl chain	16813	
1.5.1.6	tetrahydropteroylpolyglutamate	potent product inhibitor	16813	
1.5.1.6	tetrahydropteroylpolyglutamate	inhibition increases with increasing length of polyglutamyl chain; potent product inhibitor	16813	
1.5.1.6	Trypsin	-	393	
1.5.1.6	Trypsin	tryptic digestion inactivates 10-formyltetrahydrofolate dehydrogenase but not hydrolase activity	393	
1.5.1.6	Trypsin	20 min, 70% inhibition, rapid but incomplete loss of dehydrogenase activity; tryptic digestion inactivates 10-formyltetrahydrofolate dehydrogenase but not hydrolase activity	393	
1.5.1.6	Trypsin	cleavage between the two domains, inactivates 10-formyltetrahydrofolate dehydrogenase but not hydrolase and aldehyde dehydrogenase activity	393