1.2.7.4	1,10-phenanthroline	1 mM, inactivates CO/acetyl-CoA exchange activity completely but has no effect on CO oxidation	62	
1.2.7.4	2,3-Butanedione	-	1001	
1.2.7.4	5,5'-dithiobis (2-nitrobenzoate)	-	114599	
1.2.7.4	butyryl-CoA	-	270	
1.2.7.4	CN-	-	159	
1.2.7.4	CN-	0.04 mM, 60% inhibition within 10 s, CO reverses inhibition	159	
1.2.7.4	CN-	KCN, reversible	159	
1.2.7.4	CN-	reversible	159	
1.2.7.4	CN-	CO and COS protect from inhibition; CO, CO2 and COS reverse inhibition	159	
1.2.7.4	CN-	CO, CO2 and COS reverse inhibition; dithionite slows the inhibition, but cannot reactivate the enzyme	159	
1.2.7.4	CN-	0.2 mM, 17% inhibition in the presence of air, 32% CO and 69% N2, inhibition can be removed by O2 or CO	159	
1.2.7.4	CN-	1.2 mM, 98% inhibition of acetyl-CoA/CoA exchange reaction	159	
1.2.7.4	CN-	binds directly to the C-cluster	159	
1.2.7.4	CO	-	176	
1.2.7.4	CO	inhibition of the exchange reaction between acetyl-CoA and CoA	176	
1.2.7.4	CO	45% CO in headspace, 50% inhibition	176	
1.2.7.4	CO	weak, isolated alpha subunit	176	
1.2.7.4	CO	substrate inhibition. Increasing CO concentrations in the gas phase inhibit CODH activity	176	
1.2.7.4	CoASH	-	610	
1.2.7.4	COS	rapid-equilibrium inhibitor largely competitive versus CO, uncompetitive versus methyl viologen	10854	
1.2.7.4	crotonyl-CoA	-	406	
1.2.7.4	cyanide	potent inhibitor	118	
1.2.7.4	cyanide	-	118	
1.2.7.4	cyanide	inhibitory at 5 mM; strong competitive inhibitor	118	
1.2.7.4	cyanide	0.075 mM, reversible, competitive inhibition of reduced CODHII with respect to the substrate carbon monoxide, which protects reduced CODHII against inhibition by cyanide, inhibited CODHII regains initial activity after a 15-25-min incubation at 70°C with dithionite or Ti(III) citrate under CO or N2, while slower and partial reactivation to 30-50% of the initial activity occurs with dithiothreitol or without reductants	118	
1.2.7.4	cyanide	slow binding inhibitor of CODH	118	
1.2.7.4	D-glucose	partially inhibited by incubation with 0.5 mM exogenous D-glucose	35	
1.2.7.4	dephospho-CoASH	-	48977	
1.2.7.4	desulfo-CoA	-	1409	
1.2.7.4	Glyoxaldehyde	inactivation requires enzymatic turnover; only with CO and methyl viologen as substrates	44194	
1.2.7.4	Hg+	-	1756	
1.2.7.4	KCN	-	161	
1.2.7.4	KCN	CO reverses cyanide inhibition, but promotes reaction with methyl iodide	161	
1.2.7.4	KCN	0.01 mM, 85% inhibition	161	
1.2.7.4	Mersalyl acid	-	3084	
1.2.7.4	methyl iodide	CO promotes inhibition; irreversible inhibition	9217	
1.2.7.4	methyl iodide	-	9217	
1.2.7.4	additional information	dimethylglyoxime is no inhibitor, formaldehyde and acetaldehyde does not inactivate the enzyme; not inhibited by 20 mM formaldehyde or acetaldehyde	2	
1.2.7.4	additional information	pyruvate and ATP have no effect	2	
1.2.7.4	additional information	not affected by propyl iodide, methyl iodide, carbon tetrachloride,or metal chelators; not inhibited by propyl iodide, methyl iodide, carbon tetrachloride, EDTA or nitrilotriacetate	2	
1.2.7.4	additional information	phenylglyoxal, methylglyoxal, butanedione, mersalyl acid, methyl iodide, 5,5'-dithiobis (2-nitrobenzoate) and sodium dithionite inhibits the exchange reaction between CO and acetyl-CoA	2	
1.2.7.4	additional information	inhibition data are interpreted in terms of two binding sites for CO on CO dehydrogenase	2	
1.2.7.4	N2O	inhibition of the exchange reaction between acetyl-CoA and CoA	1327	
1.2.7.4	O2	-	9	
1.2.7.4	PCMB	-	78	
1.2.7.4	pivaloylpantetheine-SH	-	49356	
1.2.7.4	potassium cyanide	competitive inhibitor of reduced CODHII with respect to the substrate CO, inhibition of dithionite- or Ti(III) citrate-reduced CODHII by potassium cyanide is fully reversible since the enzyme can be completely reactivated, sodium sulfide has no effect on the reactivation of cyanide-inhibited CODHII in the presence of dithionite	2095	
1.2.7.4	propionyl-CoA	-	350	
1.2.7.4	S2-	partial inhibitor	1009	
1.2.7.4	SCN-	binds to C-center, mixed partial inhibition	1032	
1.2.7.4	Sulfide	partial	318	
1.2.7.4	thionin	-	55510