1.14.13.148 3-dimethylaminopropan-1-ol inhibitory at concentrations above about 1 mM 86277 1.14.13.148 3-dimethylaminopropan-2-ol inhibitory at concentrations above about 1 mM 86278 1.14.13.148 Ca2+ - 15 1.14.13.148 chlorpromazine - 727 1.14.13.148 Co2+ - 23 1.14.13.148 Cu2+ 0.2 mM Cu2+ inhibits the enzyme strongly without any preincubation 19 1.14.13.148 diethylmethylamine inhibitory at concentrations above about 1 mM 9589 1.14.13.148 ethyldimethylamine inhibitory at concentrations above about 1 mM 21838 1.14.13.148 additional information the enzyme is not inhibited by CO, cyanide or SKF 525-A (2-diethylaminoethyl 2,2-diphenylvalerate hydrochloride), nor by chelating agents 2 1.14.13.148 additional information 10 mM EDTA, 1 mM potassium cyanide and 1 mM sodium azide do not inhibit the enzyme. Bubbling the enzyme solution with CO for 2 min at 0°C or including CO (CO:O2 ratio 1:1) during the tests has no effect on enzyme activity 2 1.14.13.148 additional information enzyme reactions are not inhibited by gas phase containing up to 80% carbon monoxide/20% oxygen mixture 2 1.14.13.148 N,N-dimethyl-2-chloroethylamine inhibitory at concentrations above about 1 mM 86279 1.14.13.148 N,N-dimethylethanolamine inhibitory at concentrations above about 1 mM 4097 1.14.13.148 N,N-dimethylethylenediamine inhibitory at concentrations above about 1 mM 86275 1.14.13.148 N,N-dimethylpropylenediamine inhibitory at concentrations above about 1 mM 86276 1.14.13.148 N-ethylmaleimide preincubation of the enzyme for 15 min at 14°C, pH 7.7, in the presence of 1.0 mM N-ethylmaleimide inhibits the enzymatic activity approximately by 25% 49 1.14.13.148 p-chloromercuribenzoate preincubation of the enzyme for 15 min at 14°C, pH 7.7, in the presence of 0.2 mM p-chloromercuribenzoate inhibits the enzymic activity approximately by 90% 43 1.14.13.148 prochlorperazine - 9603 1.14.13.148 Thiourea - 844 1.14.13.148 Thiourea thiourea reduces ethionamide oxygenation to ethionamide S-oxide by an average of 73.5% in liver and 76.9% in lung 844 1.14.13.148 triethylamine inhibitory at concentrations above about 1 mM 10892 1.14.13.148 Zn2+ - 14