1.14.11.4	2-oxoglutarate	competitive substrate inhibition	34	
1.14.11.4	Adrenochrome	slight	15613	
1.14.11.4	Ca2+	-	15	
1.14.11.4	catechol	-	156	
1.14.11.4	Cd2+	-	52	
1.14.11.4	CO2	-	28	
1.14.11.4	Cu2+	-	19	
1.14.11.4	dehydroascorbate	-	434	
1.14.11.4	dipyridyl	a non-specific hydroxylase inhibitor; a non-specific hydroxylase inhibitor; a non-specific hydroxylase inhibitor	12878	
1.14.11.4	DL-Serine 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide	most potent	93286	
1.14.11.4	dopamine	-	242	
1.14.11.4	ephedrine	slight	20259	
1.14.11.4	epinephrine	-	1141	
1.14.11.4	homogentisic acid	-	30076	
1.14.11.4	Hydroxylysine-rich peptides	-	96619	
1.14.11.4	iodoacetamide	-	67	
1.14.11.4	L-alpha-hydroxyglutarate	the enzyme activity is inhibited by L-alpha-hydroxyglutarate but not its enantiomer D-alpha-hydroxyglutarate	224391	
1.14.11.4	malaoxon	mechanism of inhibition	6153	
1.14.11.4	malathion	mechanism of inhibition	1888	
1.14.11.4	minoxidil	0.4 mM inhibits LH1 completely, 1 mM inhibits LH2b and LH3 incompletely	9671	
1.14.11.4	minoxidil	specific inhibition of lysyl hydroxylases; specific inhibition of lysyl hydroxylases; specific inhibition of lysyl hydroxylases	9671	
1.14.11.4	additional information	the endoplasmic reticulum complex including SC65 and prolyl 3-hydroxylase 3affects the activity of lysyl-hydroxylase 1 potentially through interactions with the enzyme and/or cyclophilin B. Loss of Sc65 in the mouse results in instability of this complex, altered collagen lysine hydroxylation and cross-linking leading to connective tissue defects that include low bone mass and skin fragility, while it has no effect on prolyl 3-hydroxylation. CRTAP, a non-enzymic member of the Leprecan family of proteins which includes Synaptonemal Complex 65 (SC65) and the prolyl 3-hydroxylases (P3H1, P3H2 and P3H3), is an essential third subunit of a complex with prolyl 3-hydroxylase 1 (aka LEPRECAN) and cyclophilin B (CYPB) in the endoplasmic reticulum, forming the so-called collagen prolyl 3-hydroxylation complex	2	
1.14.11.4	N-ethylmaleimide	-	49	
1.14.11.4	NaCl	reduces the activity of the isozymes LH1, LH2a, LH2b, and LH3 with most of the synthetic nonpeptide substrates tested, in some cases the isozyme is activated or completely inhibited, overview	42	
1.14.11.4	nitroblue tetrazolium	-	2573	
1.14.11.4	norepinephrine	-	975	
1.14.11.4	p-chloromercuribenzoate	-	43	
1.14.11.4	p-mercuribenzoate	-	686	
1.14.11.4	phenylalanine	slight	429	
1.14.11.4	Phenylephedrine	slight	98184	
1.14.11.4	Pyridine 2,4-dicarboxylate	-	1592	
1.14.11.4	Pyridine 2,5-dicarboxylate	-	3361	
1.14.11.4	pyridine 2-carboxylate	-	9252	
1.14.11.4	pyrogallol	most potent	658	
1.14.11.4	SC65	directly interacts with lysyl-hydroxylase 1, LH1	224390	
1.14.11.4	succinate	-	58	
1.14.11.4	tyrosine	slight	709	
1.14.11.4	Zn2+	-	14