1.13.11.60	1,10-phenanthroline	2.5 mM, 50% inhibition	62	
1.13.11.60	2-mercaptoethanol	-	63	
1.13.11.60	4-aminobenzamidine	1 mM, over 70% inhibition	2072	
1.13.11.60	acetonitrile	10%, inactivation	981	
1.13.11.60	diclofenac	0.2 mM, over 80% inhibition	1291	
1.13.11.60	diethyldicarbonate	-	310	
1.13.11.60	dithiothreitol	-	45	
1.13.11.60	eicosatetraynoic acid	-	6735	
1.13.11.60	Emulgen 911	0.5%, inactivation	9392	
1.13.11.60	glycine	2%	72	
1.13.11.60	ICI 230,487	0.03 mM, 58% inhibition	106288	
1.13.11.60	Isopropanol	10%, inactivation	958	
1.13.11.60	linoleate-hydroxamic acid	-	21625	
1.13.11.60	linoleic acid	0.1 mM, partial inactivation, may indicate product inhibition	428	
1.13.11.60	additional information	not inhibited by 1 mM KCN. CO does not inhibit the enzyme	2	
1.13.11.60	additional information	catalysis declines due to suicide inactivation; catalysis declines due to suicide inactivation. Following column chromatography, e.g. ion exchange or zinc-affinity chromatography, hydroperoxide isomerase activity is often decreased and sometimes even undetectable by TLC, whereas 8-dioxygenase activity is always present. However, storage of the enzyme for a few days on ice often restores the hydroperoxide isomerase and appeares to increase the 7,8-linoleate diol synthase activity as well	2	
1.13.11.60	additional information	GSH (1 mM), GSSG (1 mM), EDTA (1 or 10 mM), EGTA (1 or 10 mM) and H202 (10 mM) are without effect on the 8R-dioxygenase	2	
1.13.11.60	additional information	sorbitol (0.75 M, 14%), glycerol (15%) and ethylene glycol (25%) do not inhibit the enzyme	2	
1.13.11.60	additional information	suicide inactivation, activity falls to zero within a few min although substrates were available in sufficient amounts	2	
1.13.11.60	N-tosyl-L-phenylalanyl chloromethyl ketone	1 mM, over 70% inhibition	13071	
1.13.11.60	N-[(E)-3-(3-phenoxyphenyl)prop-2-enyl]acetohydroxamic acid	i.e. BW A4C, more than 90% inhibition at 0.01 mM, about 50% inhibition at 0.001 mM	19470	
1.13.11.60	N-[(E)-3-(3-phenoxyphenyl)prop-2-enyl]acetohydroxamic acid	i.e. BW A4C	19470	
1.13.11.60	nordihydroguaiaretic acid	-	926	
1.13.11.60	paracetamol	0.2 mM, over 80% inhibition	7459	
1.13.11.60	paracetamol	0.03 mM, 44% inhibition	7459	
1.13.11.60	phenylmethanesulfonyl fluoride	0.2 mM, inhibits the 8R-dioxygenase enzyme by over 85%	827	
1.13.11.60	polyoxyethylene-10 lauryl ether	0.5%, inactivation	165831	
1.13.11.60	sodium deoxycholate	0.5%, inactivation	549	
1.13.11.60	Tetranitromethane	0.4 mM, 50% inhibition	1453	
1.13.11.60	Triton X-100	0.5%, inactivation	61	
1.13.11.60	Tween 20	0.5%, inactivation	555	
1.13.11.60	Tween 80	0.5%, inactivation	514	
1.13.11.60	Urea	1-4 M	116	
1.13.11.60	zileuton	-	3136