1.12.1.2	CdSO4	1 mM, complete inhibition	4508	
1.12.1.2	CuCl2	0.2 mM, complete inhibition	347	
1.12.1.2	cyanide	1 mM, 33% inhibition	118	
1.12.1.2	diethyl dicarbonate	chemical modification of active site His residues results in reduced enzymatic hydrogenase and diaphorase activities, pH-dependence and kinetics of modifications/inactivation	463	
1.12.1.2	DTNB	modification of thiol groups of activated enzyme results in rapid inactivation of both activities, modification of the residues of nonactivated enzyme has small effects on the enzyme activities, pH-dependence and kinetics of modifications/inactivation	554	
1.12.1.2	glutathione	above 0.1 mM: inactivation, up to 0.1 mM: activation	44	
1.12.1.2	HgCl2	0.001 mM, complete inhibition	110	
1.12.1.2	high ionic strength	200 mM phosphate buffer, 70% inhibition	3693	
1.12.1.2	iodoacetate	100 mM, 36% inhibition	93	
1.12.1.2	iodoacetate	1 mM, 10% inhibition	93	
1.12.1.2	iodoacetic acid	modification of thiol groups of activated enzyme results in rapid inactivation of both activities, modification of the residues of nonactivated enzyme has small effects on the enzyme activities, pH-dependence and kinetics of modifications/inactivation	213	
1.12.1.2	mercaptoethanol	-	1623	
1.12.1.2	additional information	not inhibited by O2, CO and chelating agents	2	
1.12.1.2	additional information	no inhibition by O2	2	
1.12.1.2	additional information	release of one FMN reduces the NAD+ reduction by 90%, but is reversible by addition of excess FMN, insensitivity towards oxygen, with all 4 CN- groups bound to the enzyme, and towards CO	2	
1.12.1.2	additional information	when light adapted cells are transferred to darkness the expression of hoxE and hoxF is only slightly affected, while the transcript levels of hoxU, hoxY and hoxH are significantly (3-5fold) decreased. Putative regulators of hox gene expression sll0359 is suppressed in dark to a similar extent as hoxU, hoxY and hoxH. The transcriptional regulator lexA shows the opposite expression pattern than that of the hox genes, since it decreases in the light. When cells in microaerobic conditions are transferred to darkness the transcript levels of hoxU, hoxY, hoxH transcripts slightly decrease	2	
1.12.1.2	Na+	-	59	
1.12.1.2	NAD+	product inhibition; product inhibition	7	
1.12.1.2	NADH	product inhibition; product inhibition	8	
1.12.1.2	Ni2+	0.5-1 mM, strong inhibition of artificial electron acceptor reduction	38	
1.12.1.2	NO	-	277	
1.12.1.2	O2	slight inhibition of NAD+ reduction and H2 evolution from NADH	9	
1.12.1.2	O2	irreversible enzyme inhibition by oxygen occurs if the CN- bound to Ni2+ is irreversibly removed or if the enzyme is reduced by NADH	9	
1.12.1.2	O2	incubation of subunits HoxHY with O2 at high potentials causes slow inactivation, but activity is recovered within seconds at potentials below -170 mV at 30°C, even in the presence of 2% O2; incubation of subunits HoxHY with O2 at high potentials causes slow inactivation, but activity is recovered within seconds at potentials below -170 mV at 30°C, even in the presence of 2% O2	9	
1.12.1.2	p-chloromercuribenzoate	0.02 mM, complete inhibition, reversed by addition of glutathione	43	
1.12.1.2	p-chloromercuribenzoate	0.15 mM, complete inhibition	43	
1.12.1.2	Sulfide	-	318	
1.12.1.2	Sulfide	0.1 mM, 10% inhibition	318	
1.12.1.2	Triethanolamine buffer	at high concentration	98582	
1.12.1.2	Tris-buffer	at high concentration	95258